The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 34,501 713,125 SH   SOLE   713,125 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 38,941 1,865,000 SH   SOLE   1,865,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 57,224 1,070,000 SH   SOLE   1,070,000 0 0
ALECTOR INC COM 014442107 26,298 1,076,039 SH   SOLE   1,076,039 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 26,763 625,000 SH   SOLE   625,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 81,461 550,000 SH   SOLE   550,000 0 0
AMYRIS INC COM NEW 03236M200 22,842 5,349,376 SH   SOLE   5,349,376 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 12,201 289,395 SH   SOLE   289,395 0 0
BEIGENE LTD SPONSORED ADR 07725L102 28,260 150,000 SH   SOLE   150,000 0 0
BIOLIFE SOLUTIONS INC COM NEW 09062W204 79,290 4,849,524 SH   SOLE   4,849,524 0 0
BLUEBIRD BIO INC COM 09609G100 67,449 1,105,000 SH   SOLE   1,105,000 0 0
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 46,749 1,730,786 SH   SOLE   1,730,786 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 120,900 1,550,000 SH   SOLE   1,550,000 0 0
CAREDX INC COM 14167L103 42,280 1,193,335 SH   SOLE   1,193,335 0 0
CODEXIS INC COM 192005106 53,497 4,692,732 SH   SOLE   4,692,732 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 29,449 980,000 SH   SOLE   980,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 19,580 266,430 SH   SOLE   266,430 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 3,882 65,000 SH   SOLE   65,000 0 0
DERMTECH INC COM 24984K105 18,900 1,428,572 SH   SOLE   1,428,572 0 0
DENALI THERAPEUTICS INC COM 24823R105 31,676 1,310,000 SH   SOLE   1,310,000 0 0
FATE THERAPEUTICS INC COM 31189P102 104,646 3,050,000 SH   SOLE   3,050,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 26,359 1,441,176 SH   SOLE   1,441,176 0 0
GENERATION BIO CO COM 37148K100 33,835 1,611,214 SH   SOLE   1,611,214 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 18,939 300,000 SH   SOLE   300,000 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 12,286 1,850,373 SH   SOLE   1,850,373 0 0
ILLUMINA INC COM 452327109 11,111 30,000 SH   SOLE   30,000 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 5,746 135,000 SH   SOLE   135,000 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 25,129 3,346,034 SH   SOLE   3,346,034 0 0
MYOKARDIA INC COM 62857M105 84,059 870,000 SH   SOLE   870,000 0 0
INVITAE CORP COM 46185L103 273,638 9,033,943 SH   SOLE   9,033,943 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 8,484 251,515 SH   SOLE   251,515 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 9,900 1,650,000 SH   SOLE   1,650,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 42,131 1,334,536 SH   SOLE   1,334,536 0 0
SANGAMO THERAPEUTICS INC COM 800677106 13,037 1,455,000 SH   SOLE   1,455,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 84,980 530,000 SH   SOLE   530,000 0 0
STOKE THERAPEUTICS INC COM 86150R107 2,860 120,000 SH   SOLE   120,000 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 4,844 75,000 SH   SOLE   75,000 0 0
TWIST BIOSCIENCE CORP COM 90184D100 45,300 1,000,000 SH   SOLE   1,000,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 9,465 750,000 SH   SOLE   750,000 0 0
ZAI LAB LTD ADR 98887Q104 15,605 190,000 SH   SOLE   190,000 0 0
ZYMEWORKS INC COM 98985W102 4,689 130,000 SH   SOLE   130,000 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 110122157 10,561 2,950,000 SH   SOLE   2,950,000 0 0