SCHEDULE 13G/A 0001352546 XXXXXXXX LIVE 1 Common Stock 02/06/2026 0001534133 CalciMedica Inc. 38942Q202 505 COAST BOULEVARD SOUTH, SUITE 307 LA JOLLA CA 92037 Rule 13d-1(c) Deerfield Mgmt, L.P. b DE 0.00 653253.00 0.00 653253.00 653253.00 N 4.34 PN Comprised of 653,253 shares of Common Stock issuable upon exercise of warrants (subject to any adjustments that may be applicable) held by Deerfield Partners, L.P., of which Deerfield Mgmt, L.P. is the general partner. Deerfield Management Company, L.P. b DE 0.00 653253.00 0.00 653253.00 653253.00 N 4.34 PN Consists of 653,253 shares of Common Stock issuable upon exercise of warrants (subject to any adjustments that may be applicable) held by Deerfield Partners, L.P., of which Deerfield Management Company, L.P. is the investment advisor. Deerfield Partners, L.P. b DE 0.00 653253.00 0.00 653253.00 653253.00 N 4.34 PN Consists of 653,253 shares of Common Stock issuable upon exercise of warrants (subject to any adjustments that may be applicable). James E. Flynn b X1 0.00 653253.00 0.00 653253.00 653253.00 N 4.34 IN Consists of 653,253 shares of Common Stock issuable upon exercise of warrants (subject to any adjustments that may be applicable) held by Deerfield Partners, L.P. CalciMedica Inc. 505 Coast Boulevard South, Suite 307, La Jolla, CA 92037 James E. Flynn, Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and Deerfield Partners, L.P. James E. Flynn, Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and Deerfield Partners, L.P., 345 Park Avenue South, 12th Floor, New York, NY 10010 Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and Deerfield Partners, L.P. - Delaware limited partnerships; James E. Flynn - United States citizen Y Deerfield Mgmt, L.P. - 653,253 shares Deerfield Management Company, L.P. - 653,253 shares Deerfield Partners, L.P. - 653,253 shares James E. Flynn - 653,253 shares Deerfield Mgmt, L.P. - 4.34% Deerfield Management Company, L.P. - 4.34% Deerfield Partners, L.P. - 4.34% James E. Flynn - 4.34% All Reporting Persons - 0 Deerfield Mgmt, L.P. - 653,253 Deerfield Management Company, L.P. - 653,253 Deerfield Partners, L.P. - 653,253 James E. Flynn - 653,253 All Reporting Persons - 0 Deerfield Mgmt, L.P. - 653,253 Deerfield Management Company, L.P. - 653,253 Deerfield Partners, L.P. - 653,253 James E. Flynn - 653,253 N Y Y Y N See Exhibit B Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Exhibit A. Joint Filing Agreement. Exhibit B. Item 8 Statement. Exhibit C. Power of Attorney (1). (1) Power of Attorney previously filed as Exhibit 24 to a Form 3 with regard to BiomX Inc. filed with the Securities and Exchange Commission on March 19, 2024 by Deerfield Private Design Fund V, L.P., Deerfield Healthcare Innovations Fund II, L.P., Deerfield Mgmt V, L.P., Deerfield Mgmt HIF II, L.P., Deerfield Management Company, L.P. and James E. Flynn. Deerfield Mgmt, L.P. /s/ Jonathan Isler 02/06/2026 Deerfield Management Company, L.P. /s/ Jonathan Isler 02/06/2026 Deerfield Partners, L.P. /s/ Jonathan Isler 02/06/2026 James E. Flynn /s/ Jonathan Isler 02/06/2026