<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: ALAFI CAPITAL CO LLC -->
          <cik>0001216017</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common Stock, par value $0.0001 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>07/22/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001534133</issuerCik>
        <issuerName>CalciMedica, Inc.</issuerName>
        <issuerCusip>38942Q202</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>505 Coast Boulevard South</com:street1>
          <com:street2>Suite 307</com:street2>
          <com:city>La Jolla</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92037</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Alafi Capital Company, LLC</reportingPersonName>
      <citizenshipOrOrganization>CA</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>1583153.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>1583153.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1583153.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>11.3</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>Row 11:
This percentage is calculated based on 13,971,990 outstanding shares of common stock of CalciMedica, Inc. (the "Issuer" or the "Company") as of May 6, 2025, as reported in the Company's Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission ("SEC") on May 14, 2025 (the "Quarterly Report").</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Christopher D. Alafi</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>1583153.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>1583153.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1583153.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>11.3</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Rows 5, 7:
Includes 1,583,153 shares of common stock held by Alafi Capital Company, LLC, for which Mr. Alafi is the managing member and for which he may be deemed to have sole voting or investment power.

Row 11:
This percentage is calculated based on 13,971,990 outstanding shares of common stock of the Company as reported in the Company's Quarterly Report.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>CalciMedica, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>505 Coast Boulevard South Suite 307 La Jolla, CA, 92037</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>This Schedule 13G is being filed on behalf of Alafi Capital Company, LLC, a California limited liability company ("Alafi Capital") and Christopher D. Alafi (together with Alafi Capital, the "Reporting Persons" and, each individually, a "Reporting Person"). Mr. Alafi is the sole managing member of Alafi Capital.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>The business address of each Reporting Person is 8 Admiral Drive, Suite 324, Emeryville, CA 94608.</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Alafi Capital is a limited liability company organized under the laws of California. Mr. Alafi is a natural person and citizen of the United States.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>The Reporting Persons beneficially own an aggregate of 1,583,153 shares of common stock of the Company.</amountBeneficiallyOwned>
        <classPercent>The Reporting Persons beneficially own an aggregate of 11.3% of the outstanding shares of common stock of the Company.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>1,583,153</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>1,583,153</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>Agreement Regarding Joint Filing of Statement on Schedule 13D or 13G (Previously Filed)</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>Alafi Capital Company, LLC</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Christopher D. Alafi</signature>
        <title>Christopher D. Alafi, as managing member of Alafi Capital Company, LLC</title>
        <date>08/05/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Christopher D. Alafi</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Christopher D. Alafi</signature>
        <title>Christopher D. Alafi</title>
        <date>08/05/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
