X0306 4 2022-11-16 0 0001533040 Phio Pharmaceuticals Corp. PHIO 0001304395 Bitterman Robert J C/O PHIO PHARMACEUTICALS CORP. 257 SIMARANO DRIVE, SUITE 101 MARLBOROUGH MA 01752 1 1 0 0 Interim Executive Chairman Series D Preferred Stock, $0.0001 par value 2022-11-16 4 P 0 1 1750.00 A 1 D The outstanding share of Series D Preferred Stock shall be redeemed in whole, but not in part, at any time: (i) if such redemption is approved by the Board of Directors in its sole discretion or (ii) automatically and effective upon the approval of an amendment to the Certificate of Incorporation to implement a reverse stock split. Upon redemption, the share of Series D Preferred Stock will receive consideration of $1,750.00 in cash. Caitlin Kontulis, attorney-in-fact 2022-11-16