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Condensed Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Balances at beginning at Dec. 31, 2020 $ 4 $ 492,436 $ 58 $ (250,441) $ 242,057
Balances at beginning (in shares) at Dec. 31, 2020 36,804,603        
Issuance of common stock upon exercise of options   272     272
Issuance of common stock upon exercise of options (in shares) 46,793        
Issuance of common stock under the Employee Stock Purchase Plan   484     484
Issuance of common stock under the Employee Stock Purchase Plan (shares) 43,018        
Stock-based compensation   8,282     8,282
Unrealized loss on available-for-sale debt securities     (42)   (42)
Net loss       (52,450) (52,450)
Balances at end at Jun. 30, 2021 $ 4 501,474 16 (302,891) 198,603
Balances at end (in shares) at Jun. 30, 2021 36,894,414        
Balances at beginning at Mar. 31, 2021 $ 4 497,561 50 (276,216) 221,399
Balances at beginning (in shares) at Mar. 31, 2021 36,890,970        
Issuance of common stock upon exercise of options   31     31
Issuance of common stock upon exercise of options (in shares) 3,444        
Stock-based compensation   3,882     3,882
Unrealized loss on available-for-sale debt securities     (34)   (34)
Net loss       (26,675) (26,675)
Balances at end at Jun. 30, 2021 $ 4 501,474 16 (302,891) 198,603
Balances at end (in shares) at Jun. 30, 2021 36,894,414        
Balances at beginning at Dec. 31, 2021 $ 4 514,794 (102) (359,767) 154,929
Balances at beginning (in shares) at Dec. 31, 2021 37,758,797        
Issuance of common stock through "at-the-market" offering, net of underwriter discount and issuance costs   3,509     3,509
Issuance of common stock through "at-the-market" offering, net of underwriter discount and issuance costs (in shares) 700,000        
Issuance of common stock upon exercise of options   76     76
Issuance of common stock upon exercise of options (in shares) 16,666        
Issuance of common stock under the Employee Stock Purchase Plan   177     177
Issuance of common stock under the Employee Stock Purchase Plan (shares) 115,973        
Stock-based compensation   9,824     9,824
Unrealized loss on available-for-sale debt securities     (559)   (559)
Net loss       (52,753) (52,753)
Balances at end at Jun. 30, 2022 $ 4 528,380 (661) (412,520) 115,203
Balances at end (in shares) at Jun. 30, 2022 38,591,436        
Balances at beginning at Mar. 31, 2022 $ 4 522,893 (470) (384,643) 137,784
Balances at beginning (in shares) at Mar. 31, 2022 38,591,436        
Stock-based compensation   5,487     5,487
Unrealized loss on available-for-sale debt securities     (191)   (191)
Net loss       (27,877) (27,877)
Balances at end at Jun. 30, 2022 $ 4 $ 528,380 $ (661) $ (412,520) $ 115,203
Balances at end (in shares) at Jun. 30, 2022 38,591,436