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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Cash Flows from Operating Activities    
Net loss $ (63,328) $ (47,371)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,805 1,218
Loss on disposal of property and equipment   7
Stock-based compensation 9,353 4,013
Preferred stock warrant liability revaluation   123
Accretion of discount on investments (63) (686)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,170) (2,714)
Accounts payable 38 1,450
Accrued expenses (93) 1,511
Other current liabilities 932 (11)
Deferred rent 3,952 141
Net cash used in operating activities (48,574) (42,319)
Cash Flows from Investing Activities    
Purchase of property and equipment (3,726) (1,822)
Purchase of investments (163,881) (84,160)
Proceeds from maturities of investments 63,110 50,000
Change in deposits 127 92
Net cash used in investing activities (104,370) (35,890)
Cash Flows from Financing Activities    
Proceeds from the issuance of common stock under the Employee Stock Purchase Plan 1,012 133
Proceeds from exercise of stock options 1,131 249
Proceeds from public offering, net 126,688 133,633
Principal payments on capital lease obligations (35) (36)
Payments of initial offering costs (364) (2,848)
Net cash provided by financing activities 128,432 131,131
Net change in cash, cash equivalents and restricted cash (24,512) 52,922
Cash, cash equivalents and restricted cash, beginning of period 159,236 114,504
Cash, cash equivalents and restricted cash, end of period 134,724 167,426
Supplemental Disclosure of Cash Flow Information    
Cash paid for interest 3 5
Cash paid for income taxes 1 1
Supplemental Schedule of Non-Cash Investing and Financing Activities    
Costs related to public offering included in accounts payable and accrued liabilities 269  
Conversion of redeemable convertible preferred stock to common stock   209,669
Reclassification of redeemable convertible preferred stock warrant liability to additional paid-in capital   503
Vesting of early exercised common stock options 4 $ 8
Purchases of property and equipment included in accounts payable and accrued liabilities $ 91