<SEC-DOCUMENT>0001140361-18-045489-index.html : 20181220
<SEC-HEADER>0001140361-18-045489.hdr.sgml : 20181220
<ACCEPTANCE-DATETIME>20181220165017
ACCESSION NUMBER:		0001140361-18-045489
CONFORMED SUBMISSION TYPE:	S-8 POS
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20181220
DATE AS OF CHANGE:		20181220
EFFECTIVENESS DATE:		20181220

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Express Scripts Holding Co.
		CENTRAL INDEX KEY:			0001532063
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				452884094
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8 POS
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-180507
		FILM NUMBER:		181246727

	BUSINESS ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121
		BUSINESS PHONE:		314-996-0900

	MAIL ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Aristotle Holding, Inc.
		DATE OF NAME CHANGE:	20111005
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8 POS
<SEQUENCE>1
<FILENAME>forms8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: forms8.htm

</DOCUMENT>
</SEC-DOCUMENT>