<SEC-DOCUMENT>0000950138-18-000185-index.html : 20180302
<SEC-HEADER>0000950138-18-000185.hdr.sgml : 20180302
<ACCEPTANCE-DATETIME>20180302161323
ACCESSION NUMBER:		0000950138-18-000185
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20180223
FILED AS OF DATE:		20180302
DATE AS OF CHANGE:		20180302

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Seiz Brian
		CENTRAL INDEX KEY:			0001732205

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35490
		FILM NUMBER:		18662119

	MAIL ADDRESS:	
		STREET 1:		C/O EXPRESS SCRIPTS HOLDING COMPANY
		STREET 2:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Express Scripts Holding Co.
		CENTRAL INDEX KEY:			0001532063
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				452884094
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121
		BUSINESS PHONE:		314-996-0900

	MAIL ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Aristotle Holding, Inc.
		DATE OF NAME CHANGE:	20111005
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
Document 1 - file: edgar.html

Document 1 - RAW XML: edgar.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>seizpoa_03022018.txt
<DESCRIPTION>POWER OF ATTORNEY FOR BRIAN SEIZ
<TEXT>
Document 2 - file: seizpoa_03022018.txt

</DOCUMENT>
</SEC-DOCUMENT>