Preferred Stock (Details) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended		12 Months Ended
	Sep. 13, 2021	Dec. 31, 2021	Sep. 30, 2021	Dec. 31, 2021	Dec. 31, 2020	Jan. 14, 2019	Apr. 20, 2018
Class of Stock [Line Items]
Preferred stock, shares authorized (in shares)		5,000,000		5,000,000	5,000,000
Preferred stock, par value (in usd per share)		$ 0.001		$ 0.001	$ 0.001
Net proceeds from issuance of preferred stock and warrants	$ 50,600			$ 50,585	$ 0
Common Stock
Class of Stock [Line Items]
Series 7 Preferred Stock converted to common stock (in shares)		7,600,000	7,600,000	7,600,000
Registered Direct Offering
Class of Stock [Line Items]
Subscription price (in usd per share)	$ 920
Original issuance discount percentage	8.00%
Aggregate subscription value	$ 54,100
Series 4 Convertible Preferred Stock
Class of Stock [Line Items]
Preferred stock, shares authorized (in shares)		10,415		10,415	10,415		10,415
Preferred stock, par value (in usd per share)							$ 1,000
Series preferred stock conversion value (in shares)							$ 828.00
Preferred stock, shares outstanding (in shares)		1		1	1
Series 5 Convertible Preferred Stock
Class of Stock [Line Items]
Preferred stock, shares authorized (in shares)		12,000		12,000	12,000	12,000
Preferred stock, par value (in usd per share)						$ 1,000
Series preferred stock conversion value (in shares)						$ 149.85
Preferred stock, shares outstanding (in shares)		126		126	126
Series 7 Preferred Stock
Class of Stock [Line Items]
Preferred stock, shares outstanding (in shares)		49,250		49,250
Mezzanine equity, convertible preferred stock, shares authorized (in shares)	58,750	58,750		58,750	58,750
Mezzanine equity, convertible preferred shares, par value per share (in usd per share)	$ 0.001
Mezzanine equity, convertible preferred shares, stated value per share (in usd per share)	$ 1,000
Mezzanine equity, convertible preferred shares, maximum voting power percentage	19.99%
Mezzanine equity, convertible preferred shares, conversion price (in usd per share)	$ 1.25
Series 7 Preferred Stock converted to common stock (in shares)		9,500	9,500
Mezzanine equity, convertible preferred stock, shares outstanding (in shares)		49,250		49,250	0