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Warrants (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 13, 2021
Feb. 16, 2021
Feb. 12, 2021
Feb. 11, 2021
Jan. 24, 2021
Mar. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Dec. 31, 2020
Warrants (Textual)                  
Common stock, par value (in usd per share)             $ 0.001 $ 0.001 $ 0.001
Number of shares sold under offering (in shares)   15,800,000   3,000,000          
Series 7 Convertible Preferred Stock                  
Warrants (Textual)                  
Mezzanine equity, convertible preferred shares, par value per share (in usd per share) $ 0.001                
Purchase Warrants                  
Warrants (Textual)                  
Exercisable warrants per common share (in shares)   1 1   1        
January 2021 Warrants                  
Warrants (Textual)                  
Common stock issued in direct offering (in shares)             13,554,838    
February 2021 Pre-Funded Warrants                  
Warrants (Textual)                  
Common stock issued in direct offering (in shares)             8,000,000    
Warrants to purchase shares of common stock (in shares)     8,000,000            
Offering price (in usd per share)     $ 1.999            
Second February 2021 Pre-Funded Warrants                  
Warrants (Textual)                  
Common stock issued in direct offering (in shares)             6,950,250    
Warrants to purchase shares of common stock (in shares)   6,950,250              
Offering price (in usd per share)   $ 2.009              
Registered Direct Offering                  
Warrants (Textual)                  
Common stock issued in direct offering (in shares)   3,000,000 7,000,000   5,800,000 15,800,000      
Subscription price (in usd per share) $ 920                
Original issuance discount percentage 8.00%                
Aggregate subscription value $ 54,050,000                
Registered Direct Offering | Series 7 Convertible Preferred Stock                  
Warrants (Textual)                  
Number of shares sold under offering (in shares) 58,750                
Registered Direct Offering | Common Stock                  
Warrants (Textual)                  
Number of shares sold under offering (in shares) 47,000,000                
Registered Direct Offering | January 2021 Pre-Funded Warrants                  
Warrants (Textual)                  
Warrants to purchase shares of common stock (in shares)         3,000,000        
Offering price (in usd per share)         $ 1.549        
Exercisable warrants per common share (in shares)         1        
Warrants                  
Warrants (Textual)                  
Warrants to purchase shares of common stock (in shares)   9,950,250 15,000,000   19,354,838        
Exercise price of warrants (in usd per share)             $ 0.001    
Warrants | Purchase Warrants                  
Warrants (Textual)                  
Offering price (in usd per share)   $ 2.01 $ 2.00   $ 1.55        
Exercise price of warrants (in usd per share)   $ 2.01 $ 2.00   $ 1.55        
Warrants | January 2021 Warrants                  
Warrants (Textual)                  
Warrants exercised for common shares (in shares)             13,554,838    
Warrants | February 2021 Pre-Funded Warrants                  
Warrants (Textual)                  
Warrants exercised for common shares (in shares)             8,000,000    
Warrants | Second February 2021 Pre-Funded Warrants                  
Warrants (Textual)                  
Warrants exercised for common shares (in shares)             6,950,250    
Warrants | Registered Direct Offering                  
Warrants (Textual)                  
Common stock issued in direct offering (in shares)   3,000,000 7,000,000   5,800,000        
Common stock, par value (in usd per share)     $ 0.001   $ 0.001        
Number of shares sold under offering (in shares) 47,000,000                
Warrants | Registered Direct Offering | Purchase Warrants                  
Warrants (Textual)                  
Warrant and rights outstanding, term   5 years 5 years   5 years        
Warrants | Registered Direct Offering | January 2021 Pre-Funded Warrants                  
Warrants (Textual)                  
Exercise price of warrants (in usd per share)   $ 0.001 $ 0.001   $ 0.001