Warrants (Details) - Warrant [Member] - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of Options Outstanding, Beginning Balance	1,083	240
Number of Options, Granted	2,459,840	5,698
Number of Options, Exercised	(92,489)	(4,035)
Number of Options, Expired	(3)	(15)
Number of Options, Cancelled		(805)
Number of Options Outstanding, Ending Balance	2,368,431	1,083
Number of Options, Exercisable	2,368,431	1,083
Weighted Average Exercise Price, Beginning Balance	$ 387.20	$ 11,616.00
Weighted Average Exercise Price, Granted	17.86	408.00
Weighted Average Exercise Price, Exercised	0.27	360.00
Weighted Average Exercise Price, Expired	18,000.00	5,616.00
Weighted Average Exercise Price, Cancelled		422.00
Weighted Average Exercise Price, Ending Balance	19.26	387.20
Weighted Average Exercise Price, Exercisable	$ 19.26	$ 387.20
Aggregate Intrinsic Value, Beginning Balance
Aggregate Intrinsic Value, Ending Balance