Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Operating activities:
Net loss	$ (130,323)	$ (63,412)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	2,141	667
Accretion of discount on available-for sale securities	1,253	53
Stock-based compensation	16,262	4,888
Reduction in the carrying amount of right-of-use assets	1,273
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(2,612)	(1,330)
Other long-term assets		96
Accounts payable	3,859	1,513
Accrued liabilities	773	4,804
Deferred rent		(366)
Operating lease liabilities	1,125
Other current liabilities	139
Net cash used in operating activities	(106,110)	(53,087)
Investing activities:
Purchases of property and equipment	(1,654)	(464)
Purchases of available-for-sale securities	(225,601)	(82,700)
Proceeds from sale of available-for-sale securities	5,993
Proceeds from maturities of available-for-sale securities	133,026
Net cash used in investing activities	(88,236)	(83,164)
Financing activities:
Proceeds from the exercise of common stock options	1,610	22
Proceeds from employee stock purchase plan	185
Proceeds from Paycheck Protection Program loan		500
Repayments of Paycheck Protection Program loan		(500)
Proceeds from issuance of redeemable convertible preferred stock (including $13,900 of proceeds from the related parties)		102,000
Payments of issuance costs related to redeemable convertible preferred stock		(5,193)
Proceeds from issuance of common stock upon initial public offering, net of underwriting discounts and commissions		267,021
Payments of offering costs related to initial public offering		(2,974)
Net cash provided by financing activities	1,795	360,876
(Decrease) increase in cash, cash equivalents, and restricted cash	(192,551)	224,625
Effect of exchange rate changes on cash, cash equivalents and restricted cash	(5)	9
Cash, cash equivalents, and restricted cash at beginning of year	268,565	43,931
Cash, cash equivalents, and restricted cash at end of year	76,009	268,565
Supplemental disclosures of cash flow information:
Cash paid for amounts included in the measurement of lease liability	996
Non-cash investing and financing activities:
Reclassification of redeemable convertible preferred stock to common stock upon initial public offering		241,418
Accretion on redeemable convertible preferred stock		705
Right-of-use assets obtained in exchange for lease liability	21,084
Leasehold improvements obtained in exchange for tenant improvement allowance from lessors	10,860
Purchase of property and equipment included in accounts payable and accrued liabilities	$ 5,540
Beneficial conversion feature recognized upon issuance of redeemable convertible preferred stock		6,297
Deemed dividend arising from conversion of beneficial conversion feature		$ 6,219