Exhibit 107.1

Calculation of Filing Fee Table

Registration Statement on Form S-3

(Form Type)

Annexon, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

	Security Type	Security Class Title	Fee Calculation or Carry Forward Rule	Amount Registered	Proposed Maximum Offering Price Per Unit(2)	Maximum Aggregate Offering Price(2)	Fee Rate	Amount of Registration Fee
Fees to Be Paid	Equity	Common Stock, par value $0.001 per share	457(c)	42,137,548(1)	$4.67	$196,782,349.16	0.0001102	$21,686
	Total Offering Amounts					$196,782,349.16		$21,686
	Total Fees Previously Paid							—
	Total Fee Offsets(3)							—
	Net Fee Due							$21,686

(1) Consists of (i) 9,013,834 shares of the registrant’s common stock issued to the selling stockholders, (ii) 24,696,206 shares of the registrant’s common stock issuable to certain of the selling stockholders upon exercise of outstanding pre-funded warrants to purchase common stock and (iii) 8,427,508 shares of the registrant’s common stock issuable to certain of the selling stockholders upon exercise of outstanding common warrants. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), the shares of common stock being registered hereunder include such indeterminate number of shares of common stock as may be issuable with respect to the shares of common stock being registered hereunder as a result of any stock dividend, stock split, recapitalization or similar transaction.

(2) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(c) of the Securities Act, on the basis of the average of the high and low prices for a share of the registrant’s common stock as reported on the Nasdaq Global Select Market on November 3, 2022, which date is within five business days prior to the filing of this Registration Statement.

(3) The Registrant does not have any fee offsets.