Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Operating activities:
Net loss	$ (103,512)	$ (54,786)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	1,077	1,075
Accretion of discount on available-for-sale securities	(3,106)	(2,932)
Stock-based compensation	9,283	9,602
Reduction in the carrying amount of right-of-use assets	731	627
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	841	(1,126)
Other non-current assets	(2,032)
Accounts payable	1,091	(1,457)
Accrued and other current liabilities	8,843	173
Operating lease liabilities	(1,342)	(1,152)
Net cash used in operating activities	(88,126)	(49,976)
Investing activities:
Purchases of property and equipment	(89)
Purchases of available-for-sale securities	(120,509)	(266,183)
Proceeds from maturities of available-for-sale securities	291,300	92,300
Net cash provided by (used in) investing activities	170,702	(173,883)
Financing activities:
Proceeds from the exercise of common stock options	62	388
Proceeds from Employee Stock Purchase Plan purchases	182	215
Proceeds from the issuance of common stock		39,737
Proceeds from the issuance of common stock and pre-funded warrants, net of commissions		117,500
Payment of financing costs	(32)	(1,776)
Net cash provided by financing activities	212	156,064
Increase (decrease) in cash, cash equivalents and restricted cash	82,788	(67,795)
Effect of exchange rate changes on cash, cash equivalents and restricted cash	2	(11)
Cash, cash equivalents and restricted cash
Beginning of period	50,530	226,142
End of period	133,320	158,336
Supplemental disclosure of cash flow information:
Cash paid for amounts included in the measurement of lease liability	2,518	2,432
Non-cash investing and financing activities:
Deferred offering costs included in accounts payable and accrued liabilities		$ 320
Deferred offering costs included in other non-current assets	81
Deemed dividend on modification of common stock warrants	$ 1,857