Stock-Based Compensation - Summary of Stock Option Activity (Details) $ / shares in Units, $ in Thousands	9 Months Ended	12 Months Ended
	Sep. 30, 2025 USD ($) $ / shares shares	Dec. 31, 2024 USD ($) $ / shares shares
2011 Plan, 2019 Plan and Inducement Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Outstanding Options, Number of Shares, Beginning Balance | shares	8,607,718
Outstanding Options, Number of Shares, granted | shares	4,617,500
Outstanding Options, Number of Shares, exercised | shares	(118,511)
Outstanding Options, Number of Shares, forfeited or expired | shares	(304,948)
Outstanding Options, Number of Shares, Ending Balance | shares	12,801,759	8,607,718
Options vested and exercisable, Number of Shares | shares	6,602,404
Outstanding Options, Weighted-Average Exercise Price, Beginning Balance | $ / shares	$ 5.07
Outstanding Options, Weighted-Average Exercise Price, granted | $ / shares	4.11
Outstanding Options, Weighted-Average Exercise Price, exercised | $ / shares	2.32
Outstanding Options, Weighted-Average Exercise Price, forfeited or expired | $ / shares	6.54
Outstanding Options, Weighted-Average Exercise Price, Ending Balance | $ / shares	4.71	$ 5.07
Options vested and exercisable, Weighted-Average Exercise Price | $ / shares	$ 5.79
Outstanding Options, Weighted-Average Remaining Contractual Term (in years)	7 years 10 months 6 days	7 years 7 months 20 days
Options vested and exercisable, Weighted-Average Remaining Contractual Term (in years)	6 years 8 months 4 days
Outstanding Options, Aggregate Intrinsic Value | $	$ 37,105	$ 21,949
Options vested and exercisable, Aggregate Intrinsic Value | $	$ 18,792
2019 Plan | Performance-Based Stock Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Outstanding Options, Number of Shares, Beginning Balance | shares	271,500
Outstanding Options, Number of Shares, Ending Balance | shares	271,500	271,500
Outstanding Options, Weighted-Average Exercise Price, Beginning Balance | $ / shares	$ 1.61
Outstanding Options, Weighted-Average Exercise Price, Ending Balance | $ / shares	$ 1.61	$ 1.61
Outstanding Options, Weighted-Average Remaining Contractual Term (in years)	8 years 5 months 12 days	9 years 2 months 12 days
Outstanding Options, Aggregate Intrinsic Value | $	$ 1,334	$ 1,133