CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Operating expenses:
Research and development	$ 9,042	$ 4,492	$ 17,427	$ 8,671
General and administrative	4,425	4,217	9,188	8,472
Total operating expenses	13,467	8,709	26,615	17,143
Loss from operations	(13,467)	(8,709)	(26,615)	(17,143)
Interest income	140	140	295	280
Interest expense	(109)		(121)
Net loss	$ (13,436)	$ (8,569)	$ (26,441)	$ (16,863)
Net loss per share - basic and diluted	$ (0.36)	$ (0.23)	$ (0.71)	$ (0.46)
Weighted-average number of common shares used in net loss per share-basic and diluted	36,992	36,992	36,992	36,983
Net loss	$ (13,436)	$ (8,569)	$ (26,441)	$ (16,863)
Unrealized (loss) gain on available-for-sale securities	(17)	(58)	(34)	34
Comprehensive loss	$ (13,453)	$ (8,627)	$ (26,475)	$ (16,829)

Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners.

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Amount after tax and reclassification adjustments, of appreciation (loss) in value of unsold available-for-sale securities, attributable to parent entity. Excludes amounts related to other than temporary impairment (OTTI) loss.

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Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS).

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