Exhibit 12.1

Computation of Ratio of Earnings to Fixed Charges

Medical Properties Trust, Inc.

The following table sets forth ratio of earnings to fixed charges and ratio of earnings to combined fixed charges and preferred dividends for the periods indicated below.

	Year Ended December 31, 2011			Year Ended December 31, 2010			Year Ended December 31, 2009			Year Ended December 31, 2008			Year Ended December 31, 2007
Income (Loss) From Continuing Operations Before Income Taxes	$	19,381		$	10,535		$	30,161		$	15,401		$	21,033
Fixed Charges		58,964			40,814			37,685			42,447			30,863
Amortization of Capitalized Interest		204			204			204			204			187
Capitalized Interest		(896	)		(63	)		—			—			(1,335	)
Earnings	$	77,653		$	51,490		$	68,050		$	58,052		$	50,748
Interest Expense/Debt Refinancing Costs	$	58,026		$	40,704		$	37,651		$	42,405		$	29,503
Portion of Rent Related to Interest		42			47			34			42			25
Capitalized Interest		896			63			—			—			1,335
Fixed Charges	$	58,964		$	40,814		$	37,685		$	42,447		$	30,863
Preferred Stock Dividends		—			—			—			—			—
Combined Fixed Charges and Preferred Stock Dividends	$	58,94		$	40,814		$	37,685		$	42,447		$	30,863
Ratio of Earnings to Fixed Charges		1.32	x		1.26	x		1.81	x		1.37	x		1.64	x
Ratio of Earnings to Combined Fixed Charges and Preferred Stock Dividends		1.32	x		1.26	x		1.81	x		1.37	x		1.64	x

Our ratio of earnings to fixed charges is computed by dividing earnings by fixed charges. Our ratio of earnings to combined fixed charges and preferred dividends is computed by dividing earnings by combined fixed charges and preferred dividends. For these purposes, “earnings” is the amount resulting from adding together income (loss) from continuing operations, fixed charges, and amortization of capitalized interest and subtracting interest capitalized. “Fixed charges” is the amount resulting from adding together interest expensed and capitalized; amortized premiums, discounts and capitalized expenses related to indebtedness; and the interest portion of rent. “Combined fixed charges and preferred dividends” is the amount resulting from adding together fixed changes and preferred dividends paid and accrued for each respective period.

Computation of Ratio of Earnings to Fixed Charges

MPT Operating Partnership, L.P.

The following table sets forth ratio of earnings to fixed charges and ratio of earnings to combined fixed charges and preferred dividends for the periods indicated below.

	Year Ended December 31, 2011			Year Ended December 31, 2010			Year Ended December 31, 2009			Year Ended December 31, 2008			Year Ended December 31, 2007
Income (Loss) From Continuing Operations Before Income Taxes	$	19,398		$	10,610		$	30,225		$	15,401		$	21,033
Fixed Charges		58,964			40,814			37,685			42,447			30,863
Amortization of Capitalized Interest		204			204			204			204			187
Capitalized Interest		(896	)		(63	)		—			—			(1,335	)
Earnings	$	77,670		$	51,565		$	68,114		$	58,052		$	50,748
Interest Expense/Debt Refinancing Costs	$	58,026		$	40,704		$	37,651		$	42,405		$	29,503
Portion of Rent Related to Interest		42			47			34			42			25
Capitalized Interest		896			63			—			—			1,335
Fixed Charges	$	58,964		$	40,814		$	37,685		$	42,447		$	30,863
Preferred Stock Dividends		—			—			—			—			—
Combined Fixed Charges and Preferred Stock Dividends	$	58,964		$	40,814		$	37,658		$	42,447		$	30,863
Ratio of Earnings to Fixed Charges		1.32	x		1.26	x		1.81	x		1.37	x		1.64	x
Ratio of Earnings to Combined Fixed Charges and Preferred Stock Dividends		1.32	x		1.26	x		1.81	x		1.37	x		1.64	x

Our ratio of earnings to fixed charges is computed by dividing earnings by fixed charges. Our ratio of earnings to combined fixed charges and preferred dividends is computed by dividing earnings by combined fixed charges and preferred dividends. For these purposes, “earnings” is the amount resulting from adding together income (loss) from continuing operations, fixed charges, and amortization of capitalized interest and subtracting interest capitalized. “Fixed charges” is the amount resulting from adding together interest expensed and capitalized; amortized premiums, discounts and capitalized expenses related to indebtedness; and the interest portion of rent. “Combined fixed charges and preferred dividends” is the amount resulting from adding together fixed changes and preferred dividends paid and accrued for each respective period.