NPORT-EX 1 NPORT_3150238452754670.htm EX-05

Schedule of Investments  (unaudited)

April 30, 2019

  

iShares® Evolved U.S. Innovative Healthcare ETF

(Percentages shown are based on Net Assets)

 

Security   Shares     Value  

Common Stocks

   
Biotechnology — 40.0%            

Abeona Therapeutics Inc.(a)

    136     $ 1,047  

Acadia Pharmaceuticals Inc.(a)(b)

    412       9,909  

Acceleron Pharma Inc.(a)

    188       7,657  

Achillion Pharmaceuticals Inc.(a)

    624       1,847  

Acorda Therapeutics Inc.(a)(b)

    204       2,132  

Aduro Biotech Inc.(a)

    184       753  

Agenus Inc.(a)

    348       894  

Alder Biopharmaceuticals Inc.(a)(b)

    312       4,240  

Alexion Pharmaceuticals Inc.(a)

    902       122,789  

Alnylam Pharmaceuticals Inc.(a)

    414       36,987  

AMAG Pharmaceuticals Inc.(a)

    128       1,429  

Amgen Inc.

    1,284       230,247  

Amicus Therapeutics Inc.(a)

    876       11,686  

AnaptysBio Inc.(a)

    68       4,945  

ANI Pharmaceuticals Inc.(a)

    28       1,988  

Arena Pharmaceuticals Inc.(a)

    256       11,712  

ArQule Inc.(a)

    498       2,973  

Arrowhead Pharmaceuticals Inc.(a)

    360       6,473  

Assembly Biosciences Inc.(a)

    88       1,389  

Atara Biotherapeutics Inc.(a)(b)

    128       4,301  

Audentes Therapeutics Inc.(a)

    128       4,837  

AVEO Pharmaceuticals Inc.(a)

    536       495  

BioCryst Pharmaceuticals Inc.(a)

    428       3,180  

Biogen Inc.(a)

    726       166,428  

BioMarin Pharmaceutical Inc.(a)

    850       72,701  

Bio-Rad Laboratories Inc., Class A(a)

    8       2,408  

Bluebird Bio Inc.(a)

    266       37,727  

Blueprint Medicines Corp.(a)(b)

    184       13,912  

Cambrex Corp.(a)

    48       2,065  

Cara Therapeutics Inc.(a)

    144       2,748  

Celgene Corp.(a)

    2,745       259,842  

Celldex Therapeutics Inc.(a)

    44       161  

ChemoCentryx Inc.(a)

    132       1,752  

Cymabay Therapeutics Inc.(a)(b)

    319       4,086  

CytomX Therapeutics Inc.(a)

    156       1,484  

Deciphera Pharmaceuticals Inc.(a)(b)

    84       1,932  

Denali Therapeutics Inc.(a)

    344       8,418  

Dicerna Pharmaceuticals Inc.(a)

    192       2,488  

Dynavax Technologies Corp.(a)

    256       1,702  

Editas Medicine Inc.(a)

    192       4,752  

Emergent BioSolutions Inc.(a)

    128       6,615  

Epizyme Inc.(a)

    240       2,978  

Esperion Therapeutics Inc.(a)

    124       5,344  

Exact Sciences Corp.(a)

    184       18,159  

Exelixis Inc.(a)

    1,288       25,322  

Fate Therapeutics Inc.(a)

    220       3,696  

FibroGen Inc.(a)

    312       14,580  

Five Prime Therapeutics Inc.(a)

    180       1,994  

Geron Corp.(a)

    492       896  

Gilead Sciences Inc.

    3,230       210,079  

GlycoMimetics Inc.(a)

    185       2,252  

Halozyme Therapeutics Inc.(a)

    480       7,742  

ImmunoGen Inc.(a)

    758       1,812  

Immunomedics Inc.(a)

    804       12,880  

Incyte Corp.(a)

    356       27,341  

Innoviva Inc.(a)

    236       3,311  

Insmed Inc.(a)

    360       10,958  

Intercept Pharmaceuticals Inc.(a)

    88       7,584  
Security   Shares     Value  
Biotechnology (continued)            

Intrexon Corp.(a)

    176     $ 762  

Ionis Pharmaceuticals Inc.(a)

    580       43,111  

Iovance Biotherapeutics Inc.(a)

    396       4,514  

Karyopharm Therapeutics Inc.(a)

    224       1,046  

Lexicon Pharmaceuticals Inc.(a)

    212       1,230  

Ligand Pharmaceuticals Inc.(a)

    96       12,082  

MacroGenics Inc.(a)

    160       2,683  

Medicines Co. (The)(a)(b)

    312       9,968  

Myriad Genetics Inc.(a)

    140       4,407  

Novavax Inc.(a)

    1,288       684  

Omeros Corp.(a)(b)

    188       3,542  

Pieris Pharmaceuticals Inc.(a)

    256       765  

PTC Therapeutics Inc.(a)

    202       7,559  

Puma Biotechnology Inc.(a)

    156       5,011  

Radius Health Inc.(a)

    200       4,404  

Regeneron Pharmaceuticals Inc.(a)

    352       120,785  

REGENXBIO Inc.(a)

    136       6,854  

Retrophin Inc.(a)

    188       3,587  

Rigel Pharmaceuticals Inc.(a)(b)

    716       1,597  

Rocket Pharmaceuticals Inc.(a)

    105       1,949  

Sage Therapeutics Inc.(a)

    227       38,188  

Sangamo Therapeutics Inc.(a)

    396       4,629  

Seattle Genetics Inc.(a)

    516       34,975  

Solid Biosciences Inc.(a)

    65       590  

Sorrento Therapeutics Inc.(a)

    276       1,007  

Spark Therapeutics Inc.(a)

    152       16,217  

Spectrum Pharmaceuticals Inc.(a)

    468       4,385  

Stemline Therapeutics Inc.(a)

    148       2,220  

Ultragenyx Pharmaceutical Inc.(a)(b)

    224       14,784  

United Therapeutics Corp.(a)

    188       19,283  

Verastem Inc.(a)

    403       858  

Vertex Pharmaceuticals Inc.(a)

    1,181       199,565  

Viking Therapeutics Inc.(a)(b)

    258       2,020  

ZIOPHARM Oncology Inc.(a)(b)

    608       2,687  
   

 

 

 
      2,000,007  
Electrical Components & Equipment — 0.2%            

Universal Display Corp.

    56       8,938  
   

 

 

 
Health Care – Products — 7.1%            

Abbott Laboratories

    1,711       136,127  

Abiomed Inc.(a)

    45       12,483  

Axogen Inc.(a)

    56       1,315  

Baxter International Inc.

    604       46,085  

Bio-Techne Corp.

    44       9,002  

Cooper Companies Inc. (The)

    68       19,715  

Glaukos Corp.(a)

    104       7,501  

Globus Medical Inc., Class A(a)

    84       3,788  

Haemonetics Corp.(a)

    52       4,539  

Hologic Inc.(a)

    144       6,679  

ICU Medical Inc.(a)

    20       4,550  

IDEXX Laboratories Inc.(a)

    92       21,344  

Insulet Corp.(a)

    84       7,245  

Integra LifeSciences Holdings Corp.(a)

    68       3,549  

Intersect ENT Inc.(a)

    72       2,339  

Intuitive Surgical Inc.(a)

    45       22,978  

Lantheus Holdings Inc.(a)

    112       2,706  

Merit Medical Systems Inc.(a)

    52       2,921  

Nevro Corp.(a)

    56       3,456  

OPKO Health Inc.(a)

    916       2,189  

Penumbra Inc.(a)

    52       6,994  
 

 

 

     1  


Schedule of Investments  (unaudited) (continued)

April 30, 2019

  

iShares® Evolved U.S. Innovative Healthcare ETF

(Percentages shown are based on Net Assets)

 

Security   Shares     Value  
Health Care – Products (continued)            

Quidel Corp.(a)

    40     $ 2,558  

Repligen Corp.(a)

    88       5,929  

ResMed Inc.

    180       18,812  
   

 

 

 
      354,804  
Health Care – Services — 1.1%            

Catalent Inc.(a)

    208       9,323  

Charles River Laboratories International Inc.(a)

    72       10,114  

IQVIA Holdings Inc.(a)

    208       28,891  

Syneos Health Inc.(a)

    112       5,256  
   

 

 

 
      53,584  
Pharmaceuticals — 50.0%            

AbbVie Inc.

    2,630       208,796  

Achaogen Inc.(a)

    152       16  

Aclaris Therapeutics Inc.(a)

    136       857  

Adamas Pharmaceuticals Inc.(a)

    92       581  

Aerie Pharmaceuticals Inc.(a)

    180       6,867  

Agios Pharmaceuticals Inc.(a)

    228       12,750  

Aimmune Therapeutics Inc.(a)(b)

    192       3,867  

Akcea Therapeutics Inc.(a)

    52       1,305  

Akebia Therapeutics Inc.(a)

    384       2,319  

Akorn Inc.(a)

    208       562  

Alkermes PLC(a)

    369       11,188  

Allergan PLC

    785       115,395  

AmerisourceBergen Corp.

    56       4,187  

Amneal Pharmaceuticals Inc.(a)

    537       6,911  

Amphastar Pharmaceuticals Inc.(a)

    132       2,850  

Anika Therapeutics Inc.(a)

    40       1,274  

Apellis Pharmaceuticals Inc.(a)

    135       2,674  

Array BioPharma Inc.(a)

    944       21,344  

Athenex Inc.(a)

    140       1,383  

Bausch Health Companies Inc.(a)(b)

    888       20,504  

Bristol-Myers Squibb Co.

    3,832       177,920  

Clovis Oncology Inc.(a)(b)

    232       4,239  

Coherus Biosciences Inc.(a)

    196       3,120  

Collegium Pharmaceutical Inc.(a)

    108       1,504  

Concert Pharmaceuticals Inc.(a)

    96       987  

Corbus Pharmaceuticals Holdings Inc.(a)(b)

    224       1,599  

Corcept Therapeutics Inc.(a)(b)

    440       5,447  

Cyclerion Therapeutics Inc.(a)

    60       914  

Cytokinetics Inc.(a)

    216       1,905  

Dermira Inc.(a)

    276       3,061  

DexCom Inc.(a)

    148       17,918  

Dova Pharmaceuticals Inc.(a)

    64       589  

Eagle Pharmaceuticals Inc./DE(a)

    56       2,879  

Eli Lilly & Co.

    2,133       249,646  

Enanta Pharmaceuticals Inc.(a)

    68       5,929  

Endo International PLC(a)

    202       1,515  

Flexion Therapeutics Inc.(a)

    156       1,654  

G1 Therapeutics Inc.(a)

    88       1,883  

Global Blood Therapeutics Inc.(a)

    220       12,188  

Heron Therapeutics Inc.(a)

    328       7,111  

Horizon Pharma PLC(a)

    214       5,463  

Intellia Therapeutics Inc.(a)

    136       2,092  

Intra-Cellular Therapies Inc.(a)

    208       2,739  

Ironwood Pharmaceuticals Inc.(a)

    600       7,134  

Jazz Pharmaceuticals PLC(a)

    40       5,191  

Johnson & Johnson

    3,740       528,088  

Jounce Therapeutics Inc.(a)

    72       409  

Kura Oncology Inc.(a)

    148       2,241  
Security   Shares     Value  
Pharmaceuticals (continued)            

La Jolla Pharmaceutical Co.(a)

    92     $ 741  

Lannett Co. Inc.(a)

    116       892  

Madrigal Pharmaceuticals Inc.(a)

    16       1,697  

MediciNova Inc.(a)(b)

    164       1,837  

Merck & Co. Inc.

    4,550       358,130  

Mirati Therapeutics Inc.(a)

    155       9,221  

Momenta Pharmaceuticals Inc.(a)

    324       4,533  

Mylan NV(a)

    1,035       27,935  

MyoKardia Inc.(a)

    140       6,717  

Nektar Therapeutics(a)

    781       25,008  

Neurocrine Biosciences Inc.(a)(b)

    468       33,808  

Pacira BioScience Inc.(a)

    152       6,053  

Paratek Pharmaceuticals Inc.(a)(b)

    124       683  

Pfizer Inc.

    8,828       358,505  

Portola Pharmaceuticals Inc.(a)(b)

    356       12,567  

PRA Health Sciences Inc.(a)

    84       8,133  

Prestige Consumer Healthcare Inc.(a)(b)

    64       1,883  

Progenics Pharmaceuticals Inc.(a)

    308       1,583  

Reata Pharmaceuticals Inc., Class A(a)

    72       5,649  

Revance Therapeutics Inc.(a)

    144       1,907  

Rhythm Pharmaceuticals Inc.(a)

    80       2,022  

Sarepta Therapeutics Inc.(a)

    310       36,251  

Supernus Pharmaceuticals Inc.(a)

    220       8,081  

Synergy Pharmaceuticals Inc.(a)

    1,136       8  

TG Therapeutics Inc.(a)

    236       1,876  

TherapeuticsMD Inc.(a)

    640       2,752  

Vanda Pharmaceuticals Inc.(a)

    224       3,649  

Voyager Therapeutics Inc.(a)

    128       2,701  

Xencor Inc.(a)

    240       7,370  

Zoetis Inc.

    816       83,101  

Zogenix Inc.(a)

    152       5,926  
   

 

 

 
      2,502,214  
Telecommunications — 0.0%            

InterDigital Inc.

    36       2,354  
   

 

 

 

Total Common Stocks — 98.4%
(Cost: $4,874,292)

      4,921,901  
   

 

 

 

Short-Term Investments

   
Money Market Funds — 4.7%            

BlackRock Cash Funds: Institutional, SL Agency Shares, 2.59%(c)(d)(e)

    160,562       160,626  

BlackRock Cash Funds: Treasury, SL Agency Shares, 2.37%(c)(d)

    72,585       72,585  
   

 

 

 
      233,211  
   

 

 

 

Total Short-Term Investments — 4.7%
(Cost: $233,193)

      233,211  
   

 

 

 

Total Investments in Securities — 103.1%
(Cost: $5,107,485)

      5,155,112  

Other Assets, Less Liabilities — (3.1)%

      (156,048
   

 

 

 

Net Assets — 100.0%

    $ 4,999,064  
   

 

 

 

 

(a) 

Non-income producing security.

(b) 

All or a portion of this security is on loan.

(c) 

Affiliate of the Fund.

(d) 

Annualized 7-day yield as of period-end.

(e) 

All or a portion of this security was purchased with cash collateral received from loaned securities.

 

 

 

2   


Schedule of Investments  (unaudited) (continued)

April 30, 2019

  

iShares® Evolved U.S. Innovative Healthcare ETF

 

Affiliates

Investments in issuers considered to be affiliates of the Fund during the nine months ended April 30, 2019, for purposes of Section 2(a)(3) of the Investment Company Act of 1940, as amended, were as follows:

 

Affiliated Issuer  

Shares

Held at

07/31/18

    Net Activity    

Shares

Held at

04/30/19

   

Value at

04/30/19

    Income    

Net Realized

Gain (Loss)

   

Change in

Unrealized

Appreciation

(Depreciation)

 

BlackRock Cash Funds: Institutional, SL Agency Shares

    80,074       80,488       160,562     $ 160,626     $ 2,076 (a)    $ 8     $ 11  

BlackRock Cash Funds: Treasury, SL Agency Shares

    53,493       19,092       72,585       72,585       849              
       

 

 

   

 

 

   

 

 

   

 

 

 
        $ 233,211     $ 2,925     $ 8     $ 11  
       

 

 

   

 

 

   

 

 

   

 

 

 

 

  (a) 

Includes securities lending income earned from the reinvestment of cash collateral from loaned securities (excluding collateral investment fees), net of fees and other payments to and from borrowers of securities, and less fees paid to BTC as securities lending agent.

 

Fair Value Measurements

Various inputs are used in determining the fair value of financial instruments. For description of the input levels and information about the Fund’s policy regarding valuation of financial instruments, refer to a recently published shareholder report. Shareholder reports are available on the Fund’s website at www.iShares.com and on the U.S. Securities and Exchange Commission website at www.sec.gov.

The following table summarizes the value of the Fund’s investments according to the fair value hierarchy as of April 30, 2019. The breakdown of the Fund’s investments into major categories is disclosed in the Schedule of Investments above.

 

      Level 1        Level 2        Level 3        Total  

Investments

                 

Assets

                 

Common Stocks

   $ 4,921,901        $        $        $ 4,921,901  

Money Market Funds

     233,211                            233,211  
  

 

 

      

 

 

      

 

 

      

 

 

 
   $ 5,155,112        $        $        $ 5,155,112  
  

 

 

      

 

 

      

 

 

      

 

 

 

 

 

     3