Consolidated Statements of Operations and Comprehensive Loss - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Statement of Comprehensive Income [Abstract]
Revenue	$ 16,363,000	$ 17,263,000
Costs and operating expenses (income):
Cost of products sold	31,910,000	32,925,000
Research and development	28,153,000	36,683,000
Selling, general and administrative	47,654,000	63,523,000
Goodwill impairment	12,026,000	0
Restructuring	2,371,000	0
Change in fair value of contingent consideration	1,053,000	(3,746,000)
Gain on sale of business	(79,465,000)	0
Total costs and operating expenses	43,702,000	129,385,000
Loss from operations	(27,339,000)	(112,122,000)
Other income (expense):
Loss on debt extinguishment	7,947,000	0
Change in fair value of warrant liability	33,000	0
Interest income	868,000	116,000
Interest expense	(5,149,000)	(5,677,000)
Total other expense, net	(12,195,000)	(5,561,000)
Loss before income taxes	(39,534,000)	(117,683,000)
Income tax expense	82,000	0
Net loss	(39,616,000)	(117,683,000)
Other comprehensive income (loss):
Unrealized gain (loss) on marketable securities	39,000	(37,000)
Foreign currency translation adjustment	(691,000)	(460,000)
Comprehensive loss	$ (40,268,000)	$ (118,180,000)
Net loss per common share, basic (in dollars per share)	$ (1.40)	$ (4.11)
Net loss per common share, diluted (in dollars per share)	$ (1.40)	$ (4.11)
Weighted average shares outstanding, basic (in shares)	28,322,753	28,654,313
Weighted average shares outstanding, diluted (in shares)	28,322,753	28,654,313