Stock-Based Compensation - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Stock Options
Outstanding at beginning of period (in shares)	3,781,636
Options granted (in shares)	562,250
Options exercised (in shares)	(35,478)
Options forfeited (in shares)	(287,049)
Outstanding at end of period (unaudited)(in shares)	4,021,359	3,781,636
Options vested and exercisable at end of period (unaudited) (in shares)	1,733,894
Weighted Average Exercise Price
Outstanding at beginning of period (in dollars per share)	$ 13.12
Options granted (in dollars per share)	2.41
Options exercised (in dollars per share)	1.85
Options forfeited (in dollars per share)	8.30
Outstanding at end of period (unaudited)(in dollars per share)	12.07	$ 13.12
Options vested and exercisable at end of period (unaudited) (in dollars per share)	$ 12.55
Stock Options Activity, Additional Disclosures
Weighted average remaining contractual life, Outstanding	7 years 8 months 12 days	7 years 7 months 6 days
Weighted average remaining contractual life, Options vested and exercisable at end of period (unaudited)	6 years 6 months
Aggregate intrinsic value, Outstanding balance at beginning of period	$ 93
Aggregate intrinsic value, Options exercised	310
Aggregate intrinsic value, Outstanding balance at end of period (unaudited)	0	$ 93
Aggregate intrinsic value, Options vested and exercisable at end of period (unaudited)	$ 0