Condensed Consolidated Statements of Stockholders’ Equity - USD ($) $ in Thousands	Total	Preferred Stock	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)
Balance at beginning of period (in shares) at Dec. 31, 2020			27,991,425
Balance at beginning of period at Dec. 31, 2020	$ 126,583		$ 28	$ 487,290	$ (361,015)	$ 280
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized loss on marketable securities	6					6
Foreign currency translation adjustment	(226)					(226)
Stock option exercises (in shares)			27,509
Stock option exercises	169			169
Stock-based compensation (in shares)			94,231
Stock-based compensation	2,910			2,910
Employee stock purchase plan shares issued (in shares)			0
Net loss	(29,181)				(29,181)
Balance at end of period (in shares) at Mar. 31, 2021			28,113,165
Balance at end of period at Mar. 31, 2021	100,261		$ 28	490,369	(390,196)	60
Balance at beginning of period (in shares) at Dec. 31, 2020			27,991,425
Balance at beginning of period at Dec. 31, 2020	126,583		$ 28	487,290	(361,015)	280
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(117,700)
Balance at end of period (in shares) at Dec. 31, 2021		6,666	27,957,223
Balance at end of period at Dec. 31, 2021	105,726	$ 0	$ 28	584,613	(478,698)	(217)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Unrealized loss on marketable securities	(57)					(57)
Foreign currency translation adjustment	$ (166)					(166)
Stock option exercises (in shares)	35,478	0	35,478
Stock option exercises	$ 66			66
Stock-based compensation (in shares)		0	192,138
Stock-based compensation	3,028			3,028
Employee stock purchase plan shares issued (in shares)		0	94,226
Employee stock purchase plan shares issued	182			182
Net loss	(40,017)				(40,017)
Balance at end of period (in shares) at Mar. 31, 2022		6,666	28,279,065
Balance at end of period at Mar. 31, 2022	$ 68,762	$ 0	$ 28	$ 587,889	$ (518,715)	$ (440)