Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Statement of Comprehensive Income [Abstract]
Revenue	$ 3,681	$ 3,591
Costs and operating expenses:
Cost of products sold	6,941	6,955
Research and development	8,003	9,370
Selling, general and administrative	14,385	16,252
Goodwill impairment	12,026	0
Restructuring	949	0
Change in fair value of contingent consideration	7	(1,153)
Total costs and operating expenses	42,311	31,424
Loss from operations	(38,630)	(27,833)
Other income (expense):
Interest income	24	40
Interest expense	(1,411)	(1,388)
Total other expense, net	(1,387)	(1,348)
Loss before income taxes	(40,017)	(29,181)
Income tax benefit	0	0
Net loss	(40,017)	(29,181)
Other comprehensive income (loss)
Unrealized (loss)/gain on marketable securities	(57)	6
Foreign currency translation adjustment	(166)	(226)
Comprehensive loss	$ (40,240)	$ (29,401)
Net loss per common share, basic (in dollars per share)	$ (1.42)	$ (1.04)
Net loss per common share, diluted (in dollars per share)	$ (1.42)	$ (1.04)
Weighted average shares outstanding, basic (in shares)	28,118,090	28,031,686
Weighted average shares outstanding, diluted (in shares)	28,118,090	28,031,686