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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Statement of Comprehensive Income [Abstract]        
Revenue $ 1,134 $ 734 $ 2,717 $ 1,521
Costs and operating expenses:        
Cost of products sold 2,663 2,435 5,857 4,611
Research and development 8,176 5,247 16,149 9,624
Selling, general and administrative 9,125 6,927 19,360 11,020
Change in fair value of contingent consideration 635   (1,584)  
Total costs and operating expenses 20,599 14,609 39,782 25,255
Loss from operations (19,465) (13,875) (37,065) (23,734)
Other income (expense):        
Change in fair value of warrant liability and embedded derivative (2,453) (1,446) (1,872) (605)
Loss on debt extinguishment   (1,398)   (1,398)
Interest income 95 143 370 208
Interest expense (1,370) (13,769) (2,724) (19,511)
Total other expense, net (3,728) (16,470) (4,226) (21,306)
Net loss (23,193) (30,345) (41,291) (45,040)
Other comprehensive income (loss)        
Unrealized (loss) gain on marketable securities (14) 6 (41) 7
Foreign currency translation adjustment 96 2 69 (12)
Comprehensive loss $ (23,111) $ (30,337) $ (41,263) $ (45,045)
Net loss per common share, basic and diluted $ (32.24) $ (45.70) $ (58.16) $ (68.21)
Weighted-average shares outstanding, basic and diluted 719,421 663,972 709,961 660,333