Business Overview and Basis of Presentation (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Business Risks and Uncertainties
Net loss	$ (27,287)	$ 222,962	$ 184,780
Accumulated deficit	797,908	825,195
Cash and cash equivalents	923,016	$ 980,972	$ 1,183,846
Short-term investments	$ 179,400