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Business Overview and Basis of Presentation (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2023
Mar. 31, 2023
Jun. 30, 2022
Mar. 31, 2022
Jun. 30, 2023
Jun. 30, 2022
Dec. 31, 2022
Accounting Policies [Abstract]              
Net loss $ (58,797) $ (68,801) $ (44,688) $ (60,598) $ (127,598) $ (105,286)  
Accumulated deficit (729,831)       (729,831)   $ (602,233)
Cash and cash equivalents 950,157   $ 1,220,273   950,157 $ 1,220,273 $ 1,183,846
Short-term investments $ 432,400       $ 432,400