<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13D" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13D/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: LEM Investments LLC -->
          <cik>0002011390</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <dateOfEvent>10/28/2024</dateOfEvent>
      <previouslyFiledFlag>false</previouslyFiledFlag>
      <issuerInfo>
        <issuerCIK>0001522222</issuerCIK>
        <issuerCUSIP>12565J308</issuerCUSIP>
        <issuerName>CLS Holdings USA, Inc.</issuerName>
        <address>
          <com:street1>516 S. 4th Street</com:street1>
          <com:city>Las Vegas</com:city>
          <com:stateOrCountry>NV</com:stateOrCountry>
          <com:zipCode>89101</com:zipCode>
        </address>
      </issuerInfo>
      <authorizedPersons>
        <notificationInfo>
          <personName>Elmer Louis Werner III</personName>
          <personPhoneNum>(602) 908-2213</personPhoneNum>
          <personAddress>
            <com:street1>6900 E Camelback Road Ste 1020</com:street1>
            <com:city>Phoenix</com:city>
            <com:stateOrCountry>AZ</com:stateOrCountry>
            <com:zipCode>85251</com:zipCode>
          </personAddress>
        </notificationInfo>
      </authorizedPersons>
    </coverPageHeader>
    <reportingPersons>
      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>ELMER LOUIS WERNER, III</reportingPersonName>
        <memberOfGroup>b</memberOfGroup>
        <fundType>WC</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>X1</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>16358109.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>16358109.00</sharedDispositivePower>
        <aggregateAmountOwned>16358109.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>9.93</percentOfClass>
        <typeOfReportingPerson>IN</typeOfReportingPerson>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonCIK>0002011390</reportingPersonCIK>
        <reportingPersonNoCIK>N</reportingPersonNoCIK>
        <reportingPersonName>LEM INVESTMENTS LLC</reportingPersonName>
        <memberOfGroup>b</memberOfGroup>
        <fundType>WC</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>AZ</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>16358109.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>16358109.00</sharedDispositivePower>
        <aggregateAmountOwned>16358109.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>9.93</percentOfClass>
        <typeOfReportingPerson>OO</typeOfReportingPerson>
      </reportingPersonInfo>
    </reportingPersons>
    <items1To7>
      <item1>
        <securityTitle>Common Stock</securityTitle>
        <issuerName>CLS Holdings USA, Inc.</issuerName>
        <issuerPrincipalAddress>
          <com:street1>516 S. 4th Street</com:street1>
          <com:city>Las Vegas</com:city>
          <com:stateOrCountry>NV</com:stateOrCountry>
          <com:zipCode>89101</com:zipCode>
        </issuerPrincipalAddress>
      </item1>
      <item2>
        <filingPersonName>The names of the persons filing this Schedule 13D are LEM Investments LLC and Elmer Louis Werner, III, the managing member of LEM Investments LLC (the "Reporting Persons").</filingPersonName>
        <principalBusinessAddress>The business address of the Reporting Persons is 6900 E Camelback Road Ste 1020, Phoenix, Arizona 85251.</principalBusinessAddress>
        <principalJob>Mr. Werner's principal business is managing his investments.  Mr. Werner conducts this business LEM Investments LLC.  LEM Investments LLC's principal business is an investment company.</principalJob>
        <hasBeenConvicted>During the past five years none of the Reporting Persons has been convicted in a criminal proceeding.</hasBeenConvicted>
        <convictionDescription>During the past five years none of the Reporting Persons has been party to a civil proceeding as a result of which it is subject to a judgment, decree or final order enjoining it from, or mandating activities subject to, federal or state securities laws, or finding it in violation of such laws.</convictionDescription>
        <citizenship>Each of the Reporting Persons is a United States citizen.</citizenship>
      </item2>
      <item3>
        <fundsSource>LEM Investments LLC purchased certain of its Common Stock with its working capital. LEM Investments LLC obtained other of its Common Stock upon the conversion of certain convertible notes representing amounts LEM Investments LLC lent to the issuer. Mr. Werner is the beneficial owner of these shares.</fundsSource>
      </item3>
      <item4>
        <transactionPurpose>The Reporting Persons purchased the Common Stock for investment purposes.

No Reporting Person has any plans or proposals that relate to or would result in any of the transactions or other matters specified in clauses (a) through (j) of Item 4 of Schedule 13D. Each Reporting Person may, at any time and from time to time, review or reconsider its position and/or change its purpose and/or formulate plans or proposals with respect thereto.</transactionPurpose>
      </item4>
      <item5>
        <percentageOfClassSecurities>Lou Werner III has the shared power to direct the vote and disposition of the shares held by LEM Investments LLC which holds 16,358,109 shares of Common Stock, representing 9.93% of the outstanding Common Stock of CLS Holdings USA, Inc.</percentageOfClassSecurities>
        <numberOfShares>Lou Werner III has the shared power to direct the vote and disposition of the shares held by LEM Investments LLC which holds 16,358,109 shares of Common Stock, representing 9.93% of the outstanding Common Stock of CLS Holdings USA, Inc.</numberOfShares>
        <transactionDesc>LEM Investments LLC sold 750,000 shares of Common Stock on October 28, 2024 at a price per share of $0.04. The sale was conducted as a private transaction to another CLS Holdings USA, Inc. shareholder.  Neither LEM Investments LLC nor Mr. Werner completed any other transactions in CLS Holdings USA, Inc. securities in the sixty days prior to October 28, 2024, in the period from October 28, 2024 through the date of filing the Schedule 13D on January 3, 2025, or in the period from January 3, 2025 through the date of filing of this Schedule 13D/A.</transactionDesc>
        <listOfShareholders>None.</listOfShareholders>
        <date5PercentOwnership>Not applicable.</date5PercentOwnership>
      </item5>
      <item6>
        <contractDescription>None.</contractDescription>
      </item6>
      <item7>
        <filedExhibits>Exhibit 99.1 Joint Filing Agreement</filedExhibits>
      </item7>
    </items1To7>
    <signatureInfo>
      <signaturePerson>
        <signatureReportingPerson>ELMER LOUIS WERNER, III</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Elmer Louis Werner, III</signature>
          <title>Elmer Louis Werner, III</title>
          <date>03/21/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>LEM INVESTMENTS LLC</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Elmer Louis Werner, III</signature>
          <title>Elmer Louis Werner, III, Member</title>
          <date>03/21/2025</date>
        </signatureDetails>
      </signaturePerson>
    </signatureInfo>
  </formData>

</edgarSubmission>
