Fair Value of Financial Instruments - Quantitative Information and Assumptions Pertaining To The Fair Value Measurement of The Level 3 Inputs (Details) $ in Thousands	Jun. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent receivable	$ 7,700	$ 9,300
Contingent consideration liabilities	111,500	86,200
Level 3
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent receivable	7,700	9,300
Contingent consideration liabilities	111,500	86,200
Level 3 | Regulatory milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent receivable	2,400	2,500
Level 3 | Royalties
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent receivable	5,300	6,800
Level 3 | Net sales targets - PYLARIFY (CVRs)
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent consideration liabilities	99,700	73,200
Level 3 | 1095 commercialization milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent consideration liabilities	1,700	1,900
Level 3 | Net sales targets - AZEDRA and 1095
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent consideration liabilities	$ 10,100	$ 11,100
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Regulatory milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.70	0.70
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Royalties | Minimum
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.10	0.10
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Royalties | Maximum
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.60	0.60
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Net sales targets - PYLARIFY (CVRs)
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	1
Level 3 | Probability adjusted discounted cash flow model | Probability of success | 1095 commercialization milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.40	0.40
Level 3 | Probability adjusted discounted cash flow model | Discount rate | Regulatory milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.20	0.17
Level 3 | Probability adjusted discounted cash flow model | Discount rate | Royalties
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.20	0.17
Level 3 | Probability adjusted discounted cash flow model | Discount rate | 1095 commercialization milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.034	0.013
Level 3 | Monte Carlo simulation | Probability of success | Net sales targets - AZEDRA and 1095 | Minimum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.40	0.40
Level 3 | Monte Carlo simulation | Probability of success | Net sales targets - AZEDRA and 1095 | Maximum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	1	1
Level 3 | Monte Carlo simulation | Discount rate | Net sales targets - PYLARIFY (CVRs)
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input		0.17
Level 3 | Monte Carlo simulation | Discount rate | Net sales targets - AZEDRA and 1095 | Minimum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.19	0.16
Level 3 | Monte Carlo simulation | Discount rate | Net sales targets - AZEDRA and 1095 | Maximum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.20	0.17