Income Taxes - Differences in Statutory Rate and Effective Rate (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Tax Disclosure [Abstract]
U.S. statutory rate	$ (15,758)	$ (2,411)	$ 6,012
Permanent items	1,764	1,176	3,210
Acquisition costs - Progenics	0	2,723	0
Recognition of deferred tax asset - assets held for sale	0	(3,000)	0
Section 162(m)	1,028	717	527
Uncertain tax positions	(8,952)	2,818	(13,156)
Other tax credits	(990)	(1,065)	(1,685)
State and local taxes	656	1,457	1,914
Impact on deferred taxes of change in tax rate	3,049	0	0
Non-deductible changes in fair value of contingent assets and liabilities	15,015	230	0
Foreign tax rate differential	23	(254)	(238)
Valuation allowance	(400)	(318)	(22)
Benefit of windfall related to stock compensation	(1,164)	(128)	(2,768)
Change in indemnification deferred tax asset	1,786	(590)	2,531
Other	184	639	635
Income tax (benefit) expense	$ (3,759)	$ 1,994	$ (3,040)