Fair Value of Financial Instruments - Quantitative Information and Assumptions Pertaining To The Fair Value Measurement of The Level 3 Inputs (Details) $ in Thousands	Mar. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Fair Value, Option, Quantitative Disclosures [Line Items]
Business Combination, Contingent Consideration, Asset	$ 12,200	$ 11,300
Contingent consideration liabilities	17,000	15,800
Level 3
Fair Value, Option, Quantitative Disclosures [Line Items]
Business Combination, Contingent Consideration, Asset	12,200	11,300
Contingent consideration liabilities	17,000	15,800
Level 3 | Regulatory milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Business Combination, Contingent Consideration, Asset	3,200	3,200
Level 3 | Royalties
Fair Value, Option, Quantitative Disclosures [Line Items]
Business Combination, Contingent Consideration, Asset	9,000	8,100
Level 3 | CVRs
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent consideration liabilities	4,600	4,200
Level 3 | 1095 commercialization milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent consideration liabilities	2,100	2,200
Level 3 | Net sales targets - AZEDRA and 1095
Fair Value, Option, Quantitative Disclosures [Line Items]
Contingent consideration liabilities	$ 10,300	$ 9,400
Level 3 | Monte-Carlo simulation | Probability of success | Net sales targets - AZEDRA and 1095 | Minimum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.40	0.40
Level 3 | Monte-Carlo simulation | Probability of success | Net sales targets - AZEDRA and 1095 | Maximum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	1	1
Level 3 | Monte-Carlo simulation | Discount rate | CVRs
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.23	0.24
Level 3 | Monte-Carlo simulation | Discount rate | Net sales targets - AZEDRA and 1095 | Minimum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.22	0.23
Level 3 | Monte-Carlo simulation | Discount rate | Net sales targets - AZEDRA and 1095 | Maximum
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.23	0.24
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Regulatory milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.90	0.90
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Royalties | Minimum
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.13	0.13
Level 3 | Probability adjusted discounted cash flow model | Probability of success | Royalties | Maximum
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.77	0.77
Level 3 | Probability adjusted discounted cash flow model | Probability of success | 1095 commercialization milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.45	0.45
Level 3 | Probability adjusted discounted cash flow model | Discount rate | Regulatory milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.23	0.24
Level 3 | Probability adjusted discounted cash flow model | Discount rate | Royalties
Fair Value, Option, Quantitative Disclosures [Line Items]
Asset measurement input	0.23	0.24
Level 3 | Probability adjusted discounted cash flow model | Discount rate | 1095 commercialization milestone
Fair Value, Option, Quantitative Disclosures [Line Items]
Liability measurement input	0.010	0.005