Revenue from Contracts with Customers - Disaggregation of Revenue (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2018 USD ($)
Disaggregation of Revenue [Line Items]
Total revenues	$ 82,630
Product revenue, net(1)
Disaggregation of Revenue [Line Items]
Total revenues	82,068
License and royalty revenues
Disaggregation of Revenue [Line Items]
Total revenues	562
U.S.
Disaggregation of Revenue [Line Items]
Total revenues	71,488
U.S. | Product revenue, net(1)
Disaggregation of Revenue [Line Items]
Total revenues	71,488
U.S. | License and royalty revenues
Disaggregation of Revenue [Line Items]
Total revenues	0
International
Disaggregation of Revenue [Line Items]
Total revenues	11,142
International | Product revenue, net(1)
Disaggregation of Revenue [Line Items]
Total revenues	10,580
International | License and royalty revenues
Disaggregation of Revenue [Line Items]
Total revenues	$ 562