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Income Taxes - Schedule of Reconciliation of Statutory Tax Rate to Effective Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Reconciliation of effective income tax rate      
Statutory tax rate (as a percent) 12.50% 12.50% 12.50%
Loss before income taxes at statutory rate $ (20,913) $ (4,913) $ (12,067)
Share-based compensation 4,461 7,841 8,972
Foreign rate differential (2,122) 5,811 7,798
Change in valuation allowance 21,455 (4,537) 11,590
Intercompany amounts (1,694) 10,707 6,234
Irish rate differential 4,926 1,817 2,511
Uncertain tax positions 602 704 811
Non-deductible lobbying expenses 775 637 683
U.S. state income taxes, net of U.S. federal benefit 598 248 1,298
In-process R&D   2,724 332
Foreign derived intangible income (10,405) (3,875) (3,125)
R&D credit (7,863) (8,488) (11,198)
Other permanent items 1,143 187 485
Total tax (benefit) provision $ (9,037) $ 8,863 $ 14,324
Effective tax rate (as a percent) 5.40% (22.50%) (14.80%)