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Revenue from Contracts with Customers - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 31, 2023
Dec. 31, 2022
Nov. 30, 2022
Oct. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Disaggregation Of Revenue [Line Items]                  
Royalty revenue             $ 1,111,795 $ 1,173,751 $ 1,038,756
Royalty                  
Disaggregation Of Revenue [Line Items]                  
Royalty revenue             $ 219,609 $ 436,179 $ 364,966
Royalty | AMPYRA                  
Disaggregation Of Revenue [Line Items]                  
Royalty revenue       $ 16,500 $ (3,200) $ 3,200      
Potential additional award to be paid     $ 1,800            
Additional award paid   $ 1,800              
Arbitration award amount paid       $ 16,500          
Repayment of royalty revenue         $ 18,300        
Royalty | AMPYRA | Subsequent Event                  
Disaggregation Of Revenue [Line Items]                  
Additional sought value for damages $ 66,000