Summary of Significant Accounting Policies - Additional Information (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2022 USD ($) Installment segment	Dec. 31, 2022 EUR (€) Installment segment	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Summary Of Significant Accounting Policies [Line Items]
Unbilled receivable	$ 72,000		$ 127,600
Allowance for doubtful accounts	200		200
Contract assets, current	8,929		13,363
Gain (loss) on foreign currency translation	$ 700		$ (300)	$ 2,400
Threshold percentage for disclosure of revenue and receivables	10.00%	10.00%	10.00%	10.00%
Advertising Expense	$ 41,400		$ 38,900	$ 25,500
Number of business segments | segment	1	1
401 (K) Plan
Summary Of Significant Accounting Policies [Line Items]
Employee contribution limit as a percentage of their eligible compensation	100.00%	100.00%
Percentage of employer contribution matched of the first employee pay	100.00%	100.00%
Maximum employee contribution limit as a percentage of their total taxable earnings	5.00%	5.00%
Employer contribution	$ 15,300		14,600	14,700
Defined Contribution Plan
Summary Of Significant Accounting Policies [Line Items]
Maximum employee contribution limit as a percentage of their total taxable earnings	40.00%	40.00%
Employer contribution	$ 5,100		5,200	$ 4,400
Per employee contribution limit | €		€ 115,000
Maximum percentage of employer contribution matched of employee's	18.00%	18.00%
Time-Based Stock Options
Summary Of Significant Accounting Policies [Line Items]
Expiration period	10 years	10 years
Number of equal annual installments for stock vested | Installment	4	4
Time-Based Stock Options | Non-employee Directors
Summary Of Significant Accounting Policies [Line Items]
Expiration period	10 years	10 years
Vesting period	1 year	1 year
Time-Based RSUs
Summary Of Significant Accounting Policies [Line Items]
Number of equal annual installments for stock vested | Installment	4	4
Minimum
Summary Of Significant Accounting Policies [Line Items]
Manufacturing Process period	10 days	10 days
Maximum
Summary Of Significant Accounting Policies [Line Items]
Manufacturing Process period	56 days	56 days
Manufacturing and royalty revenues | Minimum
Summary Of Significant Accounting Policies [Line Items]
Payment terms in number of days	30 days	30 days
Manufacturing and royalty revenues | Maximum
Summary Of Significant Accounting Policies [Line Items]
Payment terms in number of days	90 days	90 days
Manufacturing Revenue | VUMERITY
Summary Of Significant Accounting Policies [Line Items]
Percentage of cost plus	15.00%	15.00%
VUMERITY | Biogen
Summary Of Significant Accounting Policies [Line Items]
Consideration expects to receive	2022-11	2022-11
VUMERITY | Other Assets | Biogen
Summary Of Significant Accounting Policies [Line Items]
Contract assets, current			$ 5,000