CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (68,085)	$ (138,388)
Adjustments to reconcile net loss to cash flows from operating activities:
Depreciation and amortization	40,946	39,556
Share-based compensation expense	42,659	52,861
Deferred income taxes	7,665	(2,401)
Change in the fair value of contingent consideration	(12,700)	29,100
Other non-cash charges	690	675
Changes in assets and liabilities:
Receivables	19,731	30,996
Contract assets	(854)	(4,460)
Inventory	(13,782)	(3,928)
Prepaid expenses and other assets	7,645	737
Right-of-use assets	8,594	4,229
Accounts payable and accrued expenses	(68,260)	(9,918)
Contract liabilities	(2,364)	1,030
Operating lease liabilities	(6,940)	(4,593)
Other long-term liabilities	351	3,539
Cash flows used in operating activities	(44,704)	(965)
CASH FLOWS FROM INVESTING ACTIVITIES:
Additions of property, plant and equipment	(30,372)	(39,542)
Proceeds from the sale of equipment	5	291
Proceeds from contingent consideration		10,000
Purchases of investments	(85,649)	(121,809)
Sales and maturities of investments	147,859	79,104
Cash flows provided by (used in) investing activities	31,843	(71,956)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the issuance of ordinary shares under share-based compensation arrangements	6,919	12,608
Employee taxes paid related to net share settlement of equity awards	(7,406)	(9,074)
Principal payments of long-term debt	(1,421)	(1,421)
Cash flows (used in) provided by financing activities	(1,908)	2,113
NET DECREASE IN CASH AND CASH EQUIVALENTS	(14,769)	(70,808)
CASH AND CASH EQUIVALENTS—Beginning of period	203,771	266,762
CASH AND CASH EQUIVALENTS—End of period	189,002	195,954
Non-cash investing and financing activities:
Purchased capital expenditures included in accounts payable and accrued expenses	$ 4,431	$ 2,994