Share-based Compensation - Schedule of Stock Option Activity (Details) - Stock options	12 Months Ended
	Dec. 31, 2019 $ / shares shares
Number of Shares
Outstanding at the beginning of the period (in shares) | shares	14,852,457
Granted (in shares) | shares	3,812,103
Exercised (in shares) | shares	(1,515,957)
Expired (in shares) | shares	(1,104,967)
Forfeited (in shares) | shares	(807,791)
Outstanding at the end of the period (in shares) | shares	15,235,845
Exercisable at the end of the period (in shares) | shares	9,874,065
Weighted Average Exercise Price
Outstanding at the beginning of the period (in dollars per share) | $ / shares	$ 40.48
Granted (in dollars per share) | $ / shares	31.49
Exercised (in dollars per share) | $ / shares	12.55
Expired (in dollars per share) | $ / shares	48.42
Forfeited (in dollars per share) | $ / shares	42.32
Outstanding at the end of the period (in dollars per share) | $ / shares	40.34
Exercisable at the end of the period (in dollars per share) | $ / shares	$ 39.15