X0306 4 2022-03-04 0001520262 Alkermes plc. ALKS 0001675198 snyderman nancy lynn MD CONNAUGHT HOUSE 1 BURLINGTON ROAD DUBLIN 4 L2 1 Ordinary Shares 2022-03-04 4 P 0 427 23.43 A 9366 D /s/ Shantale Greenson, attorney-in-fact for Nancy Snyderman 2022-03-08