Income Taxes - Additional Information (Details) $ in Thousands, € in Millions	12 Months Ended
	Dec. 31, 2023 USD ($)	Dec. 31, 2023 EUR (€)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Income Taxes [Line Items]
Tax benefits included in discontinued operations	$ (1,400)		$ (11,100)	$ (2,500)
Cumulative unremitted earnings of overseas subsidiaries	797,000
Valuation allowance	129,296		$ 271,517	$ 249,112	$ 253,649
Valuation allowance released	143,900
Federal research and development credits	9,700
State tax credits	31,000
LTA 2017
Income Taxes [Line Items]
Notice of Assessment | €		€ 2.2
LTA 2018
Income Taxes [Line Items]
Notice of Assessment	$ 0
Minimum
Income Taxes [Line Items]
Period after loss carryforwards utilized that tax returns remain open to examination	3 years	3 years
Maximum
Income Taxes [Line Items]
Period after loss carryforwards utilized that tax returns remain open to examination	4 years	4 years
U.S. state
Income Taxes [Line Items]
Valuation allowance	$ 27,300
Operating loss carryforwards	43,200
U.S. state | Rodin Therapeutics Incorporation
Income Taxes [Line Items]
Operating loss carryforwards	6,300
U.S. federal
Income Taxes [Line Items]
Operating loss carryforwards	14,600
U.S. federal | Rodin Therapeutics Incorporation
Income Taxes [Line Items]
Operating loss carryforwards	14,600
Federal research and development credits	500
Ireland
Income Taxes [Line Items]
Income taxes payable on repatriation of unremitted earnings	70,800
Valuation allowance	102,000
Operating loss carryforwards	$ 1,300,000