CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
REVENUES:
Total revenues	$ 1,663,405	$ 1,111,795	$ 1,173,751
EXPENSES:
Cost of goods manufactured and sold (exclusive of amortization of acquired intangible assets shown below)	253,037	218,068	197,323
Research and development	270,806	272,702	290,924
Selling, general and administrative	689,751	590,751	549,610
Amortization of acquired intangible assets	35,689	36,363	38,148
Total expenses	1,249,283	1,117,884	1,076,005
OPERATING INCOME (LOSS)	414,122	(6,089)	97,746
OTHER INCOME (EXPENSE), NET:
Interest income	30,854	7,629	2,408
Interest expense	(23,032)	(13,040)	(11,219)
Change in the fair value of contingent consideration		(21,750)	(1,427)
Other (expense) income, net	(425)	2,122	219
Total other income (expense), net	7,397	(25,039)	(10,019)
INCOME (LOSS) BEFORE INCOME TAXES	421,519	(31,128)	87,727
INCOME TAX (BENEFIT) PROVISION	(97,638)	2,024	11,326
NET INCOME (LOSS) FROM CONTINUING OPERATIONS	519,157	(33,152)	76,401
DISCONTINUED OPERATIONS, NET OF TAX	(163,400)	(125,115)	(124,570)
NET INCOME (LOSS)	$ 355,757	$ (158,267)	$ (48,169)
EARNINGS (LOSS) PER ORDINARY SHARE:
Earnings (loss) per share from continuing operations - basic	$ 3.12	$ (0.2)	$ 0.47
Earnings (loss) per share from discontinued operations - basic	(0.98)	(0.76)	(0.77)
Earnings (loss) per share - basic	2.14	(0.97)	(0.3)
Earnings (loss) per share from continuing operations - diluted	3.06	(0.2)	0.46
Earnings (loss) per share from discontinued operations - diluted	(0.96)	(0.76)	(0.76)
Earnings (loss) per share - diluted	$ 2.1	$ (0.97)	$ (0.29)
WEIGHTED AVERAGE NUMBER OF ORDINARY SHARES OUTSTANDING:
Basic	166,223	163,742	160,942
Diluted	169,730	163,742	164,753
COMPREHENSIVE INCOME (LOSS):
Net Income (Loss)	$ 355,757	$ (158,267)	$ (48,169)
Holding gain (loss), net of a tax provision (benefit) of $1,195, $(973) and $(706), respectively	7,779	(7,166)	(2,374)
COMPREHENSIVE INCOME (LOSS)	363,536	(165,433)	(50,543)
Product sales, net
REVENUES:
Total revenues	919,998	777,552	627,424
Manufacturing and royalty revenues
REVENUES:
Total revenues	743,388	331,983	541,807
License revenue
REVENUES:
Total revenues		2,000	3,500
Research and development revenue
REVENUES:
Total revenues	$ 19	$ 260	$ 1,020