Share-based Compensation - Schedule of Share-based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Share-based compensation Expense
Total share-based compensation expense	$ 28,504	$ 23,377	$ 51,147	$ 41,720
Cost of goods manufactured and sold
Share-based compensation Expense
Total share-based compensation expense	2,921	2,401	5,603	4,783
Research and development
Share-based compensation Expense
Total share-based compensation expense	7,506	7,222	14,413	12,830
Selling, general and administrative
Share-based compensation Expense
Total share-based compensation expense	$ 18,077	$ 13,754	$ 31,131	$ 24,107