CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income (loss)	$ 195,220	$ (66,039)
Adjustments to reconcile net income (loss) to cash flows from operating activities:
Depreciation and amortization	37,725	38,588
Share-based compensation expense	51,147	41,720
Deferred income taxes	(38,137)	(40,815)
Change in the fair value of contingent consideration		18,197
Other non-cash charges	691	637
Changes in assets and liabilities:
Receivables	(46,511)	67,382
Contract assets	8,929	(3,123)
Inventory	(6,879)	(4,569)
Prepaid expenses and other assets	(774)	(1,986)
Right-of-use assets	8,498	8,331
Accounts payable and accrued expenses	19,995	(20,802)
Accrued sales discounts, allowances and reserves	(29,347)	(8,243)
Contract liabilities	(5,032)	(4,071)
Operating lease liabilities	(8,471)	(8,911)
Other long-term liabilities	7,354	3,076
Cash flows provided by operating activities	194,408	19,372
CASH FLOWS FROM INVESTING ACTIVITIES:
Additions of property, plant and equipment	(16,565)	(17,753)
Proceeds from the sale of equipment	3
Proceeds from contingent consideration		1,043
Return of Fountain Healthcare Partners II, L.P. investment		485
Purchases of investments	(30,284)	(194,879)
Sales and maturities of investments	240,544	109,925
Cash flows provided by (used in) investing activities	193,698	(101,179)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the issuance of ordinary shares under share-based compensation arrangements	12,000	17,992
Employee taxes paid related to net share settlement of equity awards	(25,284)	(17,583)
Principal payments of long-term debt	(1,500)	(1,500)
Cash flows used in financing activities	(14,784)	(1,091)
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS	373,322	(82,898)
CASH AND CASH EQUIVALENTS—Beginning of period	292,473	337,544
CASH AND CASH EQUIVALENTS—End of period	665,795	254,646
Non-cash investing and financing activities:
Purchased capital expenditures included in accounts payable and accrued expenses	$ 4,863	$ 4,863