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  <!-- Generated by Workiva -->
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    <own:submissionType>144</own:submissionType>
    <own:filerInfo>
      <own:filer>
        <own:filerCredentials>
          <own:cik>0002074428</own:cik>
          <own:ccc>XXXXXXXX</own:ccc>
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      </own:filer>
      <own:liveTestFlag>LIVE</own:liveTestFlag>



    </own:filerInfo>
  </own:headerData>
  <own:formData>
    <own:issuerInfo>
      <own:issuerCik>0001517413</own:issuerCik>
      <own:issuerName>Fastly, Inc.</own:issuerName>
      <own:issuerAddress>
        <com:street1>475 Brannan Street</com:street1>
        <com:street2>Suite 300</com:street2>
        <com:city>San Francisco</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>94107</com:zipCode>
      </own:issuerAddress>
      <own:issuerContactPhone>8444327859</own:issuerContactPhone>
      <own:nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Charles L. Compton III</own:nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <own:relationshipsToIssuer>
        <own:relationshipToIssuer>Director</own:relationshipToIssuer>
        <own:relationshipToIssuer>Officer</own:relationshipToIssuer>
      </own:relationshipsToIssuer>
    </own:issuerInfo>
    <own:securitiesInformation>
      <own:securitiesClassTitle>COMMON</own:securitiesClassTitle>
      <own:brokerOrMarketmakerDetails>
        <own:name>E*TRADE SECURITIES LLC.</own:name>
        <own:address>
          <com:street1>4005 Windward Plaza Dr.</com:street1>
          <com:city>Alpharetta</com:city>
          <com:stateOrCountry>GA</com:stateOrCountry>
          <com:zipCode>30005</com:zipCode>
        </own:address>
      </own:brokerOrMarketmakerDetails>
      <own:noOfUnitsSold>11344</own:noOfUnitsSold>
      <own:aggregateMarketValue>286890</own:aggregateMarketValue>
      <own:noOfUnitsOutstanding>161047199</own:noOfUnitsOutstanding>
      <own:approxSaleDate>10/16/2026</own:approxSaleDate>
      <own:securitiesExchangeName>Nasdaq</own:securitiesExchangeName>
    </own:securitiesInformation>
    <own:securitiesToBeSold>
      <own:securitiesClassTitle>COMMON</own:securitiesClassTitle>
      <own:acquiredDate>10/15/2026</own:acquiredDate>
      <own:natureOfAcquisitionTransaction>RESTRICTED</own:natureOfAcquisitionTransaction>
      <own:nameOfPersonfromWhomAcquired>FASTLY, INC.</own:nameOfPersonfromWhomAcquired>
      <own:isGiftTransaction>N</own:isGiftTransaction>
      <own:amountOfSecuritiesAcquired>11344</own:amountOfSecuritiesAcquired>
      <own:paymentDate>10/15/2026</own:paymentDate>
      <own:natureOfPayment>N/A</own:natureOfPayment>
    </own:securitiesToBeSold>
    <own:nothingToReportFlagOnSecuritiesSoldInPast3Months>N</own:nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>07/16/2026</own:saleDate>
      <own:amountOfSecuritiesSold>11412</own:amountOfSecuritiesSold>
      <own:grossProceeds>235657.8</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>07/17/2026</own:saleDate>
      <own:amountOfSecuritiesSold>2714</own:amountOfSecuritiesSold>
      <own:grossProceeds>55664.14</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>07/17/2026</own:saleDate>
      <own:amountOfSecuritiesSold>4204</own:amountOfSecuritiesSold>
      <own:grossProceeds>88704.4</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>07/17/2026</own:saleDate>
      <own:amountOfSecuritiesSold>155</own:amountOfSecuritiesSold>
      <own:grossProceeds>3394.5</own:grossProceeds>
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    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>08/04/2026</own:saleDate>
      <own:amountOfSecuritiesSold>14868</own:amountOfSecuritiesSold>
      <own:grossProceeds>371700</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>08/18/2026</own:saleDate>
      <own:amountOfSecuritiesSold>34552</own:amountOfSecuritiesSold>
      <own:grossProceeds>988187.2</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>08/19/2026</own:saleDate>
      <own:amountOfSecuritiesSold>5098</own:amountOfSecuritiesSold>
      <own:grossProceeds>122759.84</own:grossProceeds>
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    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>08/19/2026</own:saleDate>
      <own:amountOfSecuritiesSold>5400</own:amountOfSecuritiesSold>
      <own:grossProceeds>135432</own:grossProceeds>
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    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>08/19/2026</own:saleDate>
      <own:amountOfSecuritiesSold>700</own:amountOfSecuritiesSold>
      <own:grossProceeds>18235</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>08/31/2026</own:saleDate>
      <own:amountOfSecuritiesSold>15028</own:amountOfSecuritiesSold>
      <own:grossProceeds>345644</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>09/01/2026</own:saleDate>
      <own:amountOfSecuritiesSold>35501</own:amountOfSecuritiesSold>
      <own:grossProceeds>749071.1</own:grossProceeds>
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        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>09/01/2026</own:saleDate>
      <own:amountOfSecuritiesSold>18978</own:amountOfSecuritiesSold>
      <own:grossProceeds>414859.08</own:grossProceeds>
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    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>09/01/2026</own:saleDate>
      <own:amountOfSecuritiesSold>1100</own:amountOfSecuritiesSold>
      <own:grossProceeds>24871</own:grossProceeds>
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        <own:name>Charles L. Compton III</own:name>
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          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>09/02/2026</own:saleDate>
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      <own:grossProceeds>193132.36</own:grossProceeds>
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        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
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      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>09/08/2026</own:saleDate>
      <own:amountOfSecuritiesSold>2436</own:amountOfSecuritiesSold>
      <own:grossProceeds>51716.28</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:securitiesSoldInPast3Months>
      <own:sellerDetails>
        <own:name>Charles L. Compton III</own:name>
        <own:address>
          <com:street1>475 Brannan Street, Suite 300</com:street1>
          <com:city>San Francisco</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94107</com:zipCode>
        </own:address>
      </own:sellerDetails>
      <own:securitiesClassTitle>Class A Common Stock</own:securitiesClassTitle>
      <own:saleDate>09/14/2026</own:saleDate>
      <own:amountOfSecuritiesSold>50392</own:amountOfSecuritiesSold>
      <own:grossProceeds>1256272.56</own:grossProceeds>
    </own:securitiesSoldInPast3Months>
    <own:noticeSignature>
      <own:noticeDate>10/13/2026</own:noticeDate>
      <own:signature>/s/ Tara Seracka, Attorney-in-Fact for Charles L. Compton III</own:signature>
    </own:noticeSignature>
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