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Stockholders' Equity (Details)
$ / shares in Units, $ in Thousands
3 Months Ended 4 Months Ended 10 Months Ended
Mar. 01, 2022
USD ($)
Feb. 25, 2021
USD ($)
Mar. 12, 2020
USD ($)
Mar. 31, 2022
USD ($)
installment
$ / shares
shares
Sep. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
shares
May 09, 2022
USD ($)
shares
Dec. 31, 2021
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
shares
Feb. 22, 2022
$ / shares
Jun. 04, 2020
shares
Feb. 28, 2014
shares
Class of Stock [Line Items]                        
Common stock, authorized (in shares)       350,000,000       350,000,000     175,000,000  
Common stock, par value (in dollars per share) | $ / shares       $ 0.00001       $ 0.00001   $ 0.00001    
Common stock, issued (in shares)       183,386,035       177,000,963        
Common stock, outstanding (in shares)       183,386,035       177,000,963        
Preferred stock, shares authorized (in shares)       25,000,000       25,000,000        
Preferred stock, par value (in dollars per share) | $ / shares       $ 0.00001       $ 0.00001        
Preferred stock, issued (in shares)       0       0        
Preferred stock, outstanding (in shares)       0       0        
Proceeds from the issuance of common stock, net of issuance costs | $       $ 7,178   $ 29,327            
Inducement Award Program                        
Class of Stock [Line Items]                        
Number of shares granted       279,000                
Number of shares outstanding       279,000                
Share-based Payment Arrangement, Option                        
Class of Stock [Line Items]                        
Expiration period       10 years                
Share-based Payment Arrangement, Option | Share-based Compensation Award, Tranche, First Anniversary of Grant Date                        
Class of Stock [Line Items]                        
Vesting percentage       100.00%                
Share-based Payment Arrangement, Option | Share Based Compensation Award Tranche One                        
Class of Stock [Line Items]                        
Vesting period       1 year                
Vesting percentage       25.00%                
Share-based Payment Arrangement, Option | Share Based Compensation Award Tranche Two                        
Class of Stock [Line Items]                        
Vesting period       1 year                
Number of equal quarterly installments | installment       12                
Service-Based Restricted Stock Units | Share Based Compensation Award Tranche One                        
Class of Stock [Line Items]                        
Vesting period       1 year                
Vesting percentage       50.00%                
Service-Based Restricted Stock Units | Share Based Compensation Award Tranche Two                        
Class of Stock [Line Items]                        
Vesting period       6 months                
Vesting percentage       25.00%                
Award vesting grace period       1 year                
Service-Based Restricted Stock Units | Share-based Compensation Award, Tranche, First Or Third Anniversary of Grant Date                        
Class of Stock [Line Items]                        
Vesting percentage       100.00%                
Service-Based Restricted Stock Units | Share-Based Payment Arrangement, Tranche One, First Anniversary After Grant Date, Subjected To Individual Continued Service                        
Class of Stock [Line Items]                        
Vesting period       1 year                
Vesting percentage       33.33%                
Service-Based Restricted Stock Units | Share-Based Payment Arrangement, Tranche Two, Second Anniversary After Grant Date, Subjected To Individual Continued Service                        
Class of Stock [Line Items]                        
Vesting period       2 years                
Vesting percentage       33.33%                
Service-Based Restricted Stock Units | Share-Based Payment Arrangement, Tranche Three, Third Anniversary After Grant Date, Subjected To Individual Continued Service                        
Class of Stock [Line Items]                        
Vesting period       3 years                
Vesting percentage       33.33%                
Common Stock                        
Class of Stock [Line Items]                        
Common stock, outstanding (in shares)       183,386,035   158,520,089   177,000,963 148,074,085      
Issuance of common stock, net of issuance costs (in shares)       4,404,600   9,228,017            
Common Stock | At The Market Equity Offering Program Authorized February 2021                        
Class of Stock [Line Items]                        
Issuance of common stock, net of issuance costs (in shares)               21,128,065        
Proceeds from the issuance of common stock, net of issuance costs | $               $ 72,400        
Common Stock | At The Market Equity Offering Program Authorized March 2022 | Subsequent Event                        
Class of Stock [Line Items]                        
Issuance of common stock, net of issuance costs (in shares)             404,600          
Proceeds from the issuance of common stock, net of issuance costs | $             $ 800          
Minimum | Share-based Payment Arrangement, Option                        
Class of Stock [Line Items]                        
Vesting period       12 months                
Minimum | Service-Based Restricted Stock Units | Share-based Compensation Award, Tranche, First Or Third Anniversary of Grant Date                        
Class of Stock [Line Items]                        
Vesting period       1 year                
Maximum | At The Market Equity Offering Program Authorized February 2021                        
Class of Stock [Line Items]                        
Common stock sales agreement amount | $   $ 100,000                    
Maximum | At The Market Equity Offering Program Authorized March 2022                        
Class of Stock [Line Items]                        
Common stock sales agreement amount | $ $ 25,300                      
Maximum | Share-based Payment Arrangement, Option                        
Class of Stock [Line Items]                        
Vesting period       48 months                
Maximum | Service-Based Restricted Stock Units | Share-based Compensation Award, Tranche, First Or Third Anniversary of Grant Date                        
Class of Stock [Line Items]                        
Vesting period       3 years                
At The Market Equity Offering Program | Common Stock                        
Class of Stock [Line Items]                        
Issuance of common stock, net of issuance costs (in shares)           5,224,278     3,509,381      
Proceeds from the issuance of common stock, net of issuance costs | $         $ 15,900       $ 10,600      
At The Market Equity Offering Program | Maximum                        
Class of Stock [Line Items]                        
Common stock sales agreement amount | $     $ 65,000                  
2014 Plans                        
Class of Stock [Line Items]                        
Common stock, reserved for future issuance (in shares)                       1,785,000
Incremental rate at which the shares reserved for issuance increase       3.00%                
2014 Plans | Share-based Payment Arrangement, Option | Employees                        
Class of Stock [Line Items]                        
Number of shares granted       2,833,500                
2014 Plans | Performance Shares                        
Class of Stock [Line Items]                        
Number of shares granted       0                
2014 Plans | Service-Based Restricted Stock Units | Employees                        
Class of Stock [Line Items]                        
Number of shares granted (in shares)       2,914,308                
2014 Plans | Performance-Based Restricted Stock Units                        
Class of Stock [Line Items]                        
Number of shares granted (in shares)       0                
2014 Employee Stock Purchase Plan                        
Class of Stock [Line Items]                        
Common stock, reserved for future issuance (in shares)       4,981,995                
Offering period       6 months                
Purchase price at the end of offering period       85.00%                
Number of shares issued       191,146