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Inventory - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Business Acquisition [Line Items]    
Inventory amounts written down $ 5,344 $ 5,075
Inventory adjustments to previous reserves 3,200  
Keryx Biopharmaceuticals, Inc.    
Business Acquisition [Line Items]    
Inventory step-up charges $ 0 $ 8,700