Product Revenue and Reserves for Variable Consideration - Product Revenue Allowance and Reserve Categories (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2022	Mar. 31, 2021
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	$ 28,378	$ 41,363
Current provisions related to sales in current year	25,394	38,965
Adjustments related to prior year sales	647	(1,238)
Credits/payments made	(26,249)	(33,661)
Ending balance	28,170	45,429
Chargebacks and Discounts
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	1,278	802
Current provisions related to sales in current year	2,711	3,170
Adjustments related to prior year sales	(132)	3
Credits/payments made	(2,465)	(2,646)
Ending balance	1,392	1,329
Rebates, Fees and other Deductions
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	26,625	39,912
Current provisions related to sales in current year	21,324	33,643
Adjustments related to prior year sales	779	(1,241)
Credits/payments made	(22,491)	(29,098)
Ending balance	26,237	43,216
Returns
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward]
Beginning balance	475	649
Current provisions related to sales in current year	1,359	2,152
Adjustments related to prior year sales	0	0
Credits/payments made	(1,293)	(1,917)
Ending balance	$ 541	$ 884

Valuation allowances and reserves adjustments related to prior period sales.

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- Definition

A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.

+ References

No definition available.

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- Definition

Amount of valuation and qualifying accounts and reserves.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 4
-Subparagraph (SX 210.12-09(Column B))
-URI http://asc.fasb.org/extlink&oid=120395691&loc=d3e24092-122690

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 4
-Subparagraph (SX 210.12-09(Column E))
-URI http://asc.fasb.org/extlink&oid=120395691&loc=d3e24092-122690

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- Definition

Amount of increase in valuation and qualifying accounts and reserves from charge to cost and expense.

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- Definition

Amount of decrease in valuation and qualifying accounts and reserves.

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