Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Income Tax Disclosure [Abstract]

Schedule of Reconciliation of Statutory Federal Income Tax Rate to Effective Tax Rate

Following is a reconciliation of the statutory federal income rate to the Company’s effective tax rate:

	Year ended December 31,
	2015			2014
Federal tax at statutory rate		34.0	%		34.0	%
State and local tax at statutory rate		3.0			5.5
Research and development tax credits		0.4			(0.6	)
Equity compensation		(0.6	)		(1.6	)
Other permanent differences and credits		—			(0.1	)
Change in valuation allowance		(36.8	)		(37.2	)
Effective tax rate		0.0	%		0.0	%

Schedule of Significant Deferred Tax Assets and Liabilities

Significant components of the Company’s deferred tax assets and liabilities are as follows:

		December 31,
		2015			2014
	(in thousands)
Deferred tax assets:
Accrued expenses		$	912		$	559
Intangible assets			527		$	603
Restricted stock			301		$	436
Fixed assets			—		$	2
Non-qualified stock options (1)			1,558		$	440
Research and development credits			1,829		$	1,589
Net operating loss carryforward			51,356		$	30,559
Other			64		$	39
Total deferred tax assets			56,547		$	34,227
Less valuation allowance			(56,545	)		(34,227	)
Total deferred tax assets, net of valuation allowance			2			—
Deferred tax liabilities:
Fixed assets			(2	)		—
Restricted stock			—			—
Total deferred tax liabilities			(2	)		—
Net deferred tax asset		$	—		$	—