X0306 4 2022-02-28 false 0001517022 Akebia Therapeutics, Inc. AKBA 0001619834 Burke Steven Keith C/O AKEBIA THERAPEUTICS, INC 245 FIRST STREET CAMBRIDGE MA 02142 false true false false SVP, Chief Medical Officer Common Stock 2022-02-28 4 S false 7400.00 2.1548 D 163819.00 D Common Stock 2022-02-28 4 A false 60000.00 0.00 A 223819.00 D Common Stock 2022-03-01 4 S false 6556.00 2.1707 D 217263.00 D Common Stock 2022-03-01 4 S false 1100.00 2.1707 D 217663.00 D Employee Stock Option (Right to buy) 2.16 2022-02-28 4 A false 225000.00 0.00 A 2032-02-28 Common Stock 225000.00 225000.00 D This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-third of the reporting person's restricted stock units granted on February 26, 2021. The restricted stock units were granted by the Issuer pursuant to its 2014 Incentive Plan, as amended. One-third of the restricted stock units will vest on each of the first, second and third anniversaries of the grant date, subject to the reporting person's continued service with the Issuer on each vesting date. This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-third of the reporting person's restricted stock units granted on February 28, 2020. This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-third of the performance-based restricted stock units that were previously reported for the Reporting Person on a Form 4 filed on March 18, 2021. Includes 1,500 shares of the Issuers common stock purchased on December 31, 2021, under the Issuers 2014 Amended and Restated Employee Stock Purchase Plan. The options were granted by the Issuer pursuant to its 2014 Incentive Plan, as amended. The options will vest over four years: 25% of the options will vest on the first anniversary of the grant date with the remaining 75% vesting in equal quarterly installments thereafter, subject to the reporting person's continued service with the Issuer on each vesting date. /s/ Carolyn Rucci, attorney-in-fact for Steven K. Burke 2022-03-02