X0306 4 2020-05-06 0 0001515673 Ultragenyx Pharmaceutical Inc. RARE 0001648096 Pinion John Richard C/O ULTRAGENYX PHARMACEUTICAL INC. 60 LEVERONI COURT NOVATO CA 94949 0 1 0 0 See Remarks Common Stock 2020-05-06 4 F 0 248 66.26 D 48991 D Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs"). Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions. /s/ Karah Parschauer, attorney-in-fact 2020-05-08