License and Research Agreements - Schedule of Changes in Fair Value of Equity Investment (Details) - USD ($) $ in Thousands	6 Months Ended	12 Months Ended
	Jun. 30, 2022	Dec. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock, Beginning balance	$ 1,001,451
Common stock, Ending balance	693,901	$ 1,001,451
Solid and Arcturus | Common Stock
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock, Beginning balance	32,200	154,756
Common stock, Change in fair value	(19,513)	(42,713)
Common stock, Sale of shares		(79,843)
Common stock, Ending balance	$ 12,687	$ 32,200