CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 159,868	$ 307,584
Marketable debt securities	382,927	432,612
Accounts receivable, net	37,207	28,432
Inventory	21,079	16,231
Prepaid expenses and other current assets	77,461	71,745
Total current assets	678,542	856,604
Property, plant, and equipment, net	207,381	141,247
Equity investments	15,412	34,925
Marketable debt securities	163,301	258,933
Right-of-use assets	31,245	34,936
Intangible assets, net	159,196	130,788
Goodwill	44,406	44,406
Other assets	21,144	20,558
Total assets	1,320,627	1,522,397
Current liabilities:
Accounts payable	34,213	17,138
Accrued liabilities	170,355	145,555
Contract liabilities	4,437	7,609
Lease liabilities	11,631	11,066
Total current liabilities	220,636	181,368
Lease liabilities	25,902	30,904
Contract liabilities	0	1,467
Deferred tax liabilities	33,306	33,306
Liability related to the sale of future royalties	358,942	351,786
Other liabilities	3,768	1,005
Total liabilities	642,554	599,836
Stockholders’ equity:
Preferred stock - 25,000,000 shares authorized; nil outstanding as of June 30, 2022 and December 31, 2021	0	0
Common stock - 250,000,000 shares authorized; 70,010,398 and 69,344,998 shares issued and outstanding as of June 30, 2022 and December 31, 2021, respectively	70	69
Additional paid-in capital	3,071,000	2,997,497
Accumulated other comprehensive loss	(8,914)	(1,404)
Accumulated deficit	(2,384,083)	(2,073,601)
Total stockholders’ equity	678,073	922,561
Total liabilities and stockholders’ equity	$ 1,320,627	$ 1,522,397