The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AARDVARK THERAPEUTICS INC COM 002942100   1,193,661 316,621 SH   DFND   0 316,621 0
ACADIA PHARMACEUTICALS INC COM 004225108   3,219,241 144,620 SH   DFND   0 144,620 0
AGIOS PHARMACEUTICALS INC COM 00847X104   5,576,503 164,839 SH   DFND   0 164,839 0
ALKERMES PLC SHS G01767105   5,650,210 159,791 SH   DFND   0 159,791 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   4,418,490 317,877 SH   DFND   0 317,877 0
ANNEXON INC COM 03589W102   7,160,201 1,292,455 SH   DFND   0 1,292,455 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   7,975,315 127,198 SH   DFND   0 127,198 0
AUTOLUS THERAPEUTICS LTD SPON ADS 05280R100   13,110,000 9,500,000 SH   DFND   0 9,500,000 0
AXSOME THERAPEUTICS INC. COM 05464T104   3,390,372 20,059 SH   DFND   0 20,059 0
AXSOME THERAPEUTICS INC. COM 05464T104   5,915,700 35,000 SH Call DFND   0 35,000 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   9,906,664 312,316 SH   DFND   0 312,316 0
DEFINIUM THERAPEUTICS INC COM SHS 24477V105   3,779,887 199,994 SH   DFND   0 199,994 0
DYNE THERAPEUTICS INC COM 26818M108   4,679,933 258,132 SH   DFND   0 258,132 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104   3,342,713 119,340 SH   DFND   0 119,340 0
IMMUNOVANT INC COM 45258J102   5,427,714 218,507 SH   DFND   0 218,507 0
IONIS PHARMACEUTICALS INC COM 462222100   3,136,059 41,764 SH   DFND   0 41,764 0
KARYOPHARM THERAPEUTICS INC COM NEW 48576U205   295,121 52,984 SH   DFND   0 52,984 0
KARYOPHARM THERAPEUTICS INC COM NEW 48576U205   278,500 50,000 SH Call DFND   0 50,000 0
KOLIBRI GLOBAL ENERGY INC COM NEW 50043K406   22,810,697 4,154,954 SH   DFND 1,2,3 0 4,154,954 0
KOLIBRI GLOBAL ENERGY INC COM NEW 50043K406   14,710,730 2,679,550 SH   DFND 1,2 0 2,679,550 0
KRYSTAL BIOTECH INC COM 501147102   5,080,638 19,668 SH   DFND   0 19,668 0
LYFT INC CL A COM 55087P104   13,300,000 1,000,000 SH   DFND   0 1,000,000 0
MAPLIGHT THERAPEUTICS INC COM 56565P103   2,279,298 112,115 SH   DFND   0 112,115 0
MBX BIOSCIENCES INC COM 55287L101   4,342,578 145,480 SH   DFND   0 145,480 0
NEKTAR THERAPEUTICS COM NEW 640268306   7,413,512 103,037 SH   DFND   0 103,037 0
PHARVARIS N V COM N69605108   6,260,511 221,611 SH   DFND   0 221,611 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   5,139,575 15,952 SH   DFND   0 15,952 0
RELAY THERAPEUTICS INC COM 75943R102   1,806,353 181,543 SH   DFND   0 181,543 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   3,320,948 630,161 SH   DFND   0 630,161 0
SNOWFLAKE INC COM SHS 833445109   1,508,200 10,000 SH   DFND   0 10,000 0
SOLENO THERAPEUTICS INC COM 834203309   3,419,145 102,125 SH   DFND   0 102,125 0
SPRINKLR INC CL A 85208T107   13,200,000 2,200,000 SH   DFND 1,2,3 0 2,200,000 0
TECTONIC THERAPEUTIC INC COM 878972108   1,161,845 37,588 SH   DFND   0 37,588 0
UIPATH INC CL A 90364P105   31,834,312 2,867,956 SH   DFND 1,2 0 2,867,956 0
UIPATH INC CL A 90364P105   196,554,671 17,707,628 SH   DFND   0 17,707,628 0
UIPATH INC CL A 90364P105   51,415,688 4,632,044 SH   DFND 1,2,3 0 4,632,044 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   826,959 39,473 SH   DFND   0 39,473 0
WARNER BROS DISCOVERY INC COM SER A 934423104   15,579,925 567,368 SH   DFND 1,2,3 0 567,368 0
WARNER BROS DISCOVERY INC COM SER A 934423104   9,785,564 356,357 SH   DFND 1,2 0 356,357 0
WORKIVA INC COM CL A 98139A105   14,907,500 250,000 SH   DFND 1,2,3 0 250,000 0